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BESTSELLER
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What It Does
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Berberine is an extraordinarily powerful plant alkaloid clinically proven to effectively promote blood sugar balance—and weight loss. Berberine naturally increases levels of GLP-1, a key hormone that regulates fat-burning metabolism. It also activates an enzyme called AMPK (often referred to as your “metabolic master switch”) to promote appetite control, reduced fat storage and blood sugar regulation, as well as balanced cholesterol.*
Widely considered the best berberine extract in the world, Berbevis® features a next-generation phytosome delivery system that gives it 10x better absorption than other forms of berberine.*
This cutting-edge formula also includes a 300 mg dose of Greenselect®, an advanced decaffeinated green tea extract that also leverages phytosome technology and has been proven to rev up your metabolism and support weight loss of up to 30 pounds in 90 days when combined with a reduced calorie diet. Greenselect® Green Tea Phytosome™ offers a 2-fold increase in absorption and a 20% increase in plasma antioxidant potential compared to standard green tea extract.*
Additionally, a therapeutic 200 mcg dose of premium-grade, highly absorbable Albion® chromium provides synergistic support for blood sugar balance. As an essential trace mineral, chromium plays an important role in helping the body process and utilize sugar from the bloodstream for energy, a critical factor in reducing fat storage. Research shows that chromium can help improve body composition while fighting cravings that can derail your weight loss efforts.*
No other berberine supplement on the market combines these effective ingredients into one convenient formula. Durable BERBERINE offers exceptional and comprehensive support for healthy weight management, blood sugar regulation, metabolic health and cholesterol balance with just two capsules a day, and without adverse side effects.*
This synergistic combination of powerful, clinically validated ingredients:*
- Can help you lose up to 30 pounds in 90 days
- Reduces hard-to-lose visceral fat by 22% in 60 days
- Reduces body mass index (BMI) by up to 13.9%
- Can help shrink your waistline by up to 10.7%
- Boosts GLP-1 levels to help increase fat-burning
- Helps suppress appetite and promotes satiety
- Reduces insulin resistance in as little as 30 days
- Reduces fasting insulin levels by 42% in 60 days
- Promotes metabolic health and blood sugar balance
- Supports healthy cholesterol and triglyceride levels
General Product Info:
- 60 vegetarian capsules (a 30 day supply)
- Made in the USA in an FDA inspected, cGMP facility
- Every batch is 3rd party tested for safety and purity
- Packaged in premium, non-toxic amber glass bottles
- One-year return policy with free return shipping
Why It Works
+
Dr. Passero’s 20+ years of experience went into formulating Durable BERBERINE, which features a potent 1,100 mg daily dose of a standardized, highly absorbable berberine extract called Berbevis® Berberine Phytosome™. Widely recognized as one of the best berberine extracts in the world, this phytosome-form extract utilizes an innovative delivery system to provide up to 10x better absorption than the berberine extracts found in most supplements.*
Berberine’s powerful weight loss promoting, metabolic boosting and blood sugar balancing effects are synergistically enhanced with 300 mg of clinically studied, caffeine-free Greenselect® Green Tea Phytosome™ and a therapeutic 200 mcg dose of Albion® chromium for even greater benefits.*
What Is Berberine and How Does It Work?
Berberine is an extraordinarily powerful plant alkaloid found in some of nature’s most revered medicinal herbs, including barberry, goldenseal and Oregon grape root. Extensive scientific research shows that, among a slew of health benefits, berberine excels at promoting blood sugar balance—and weight loss—via its regulating effects on metabolism.*
Berberine activates an energy-stabilizing enzyme called AMPK, often referred to as the “metabolic master switch,” which helps maintain balanced blood sugar levels and overall metabolic health. In addition, berberine enhances insulin sensitivity, which means it helps cells respond more effectively to the hormone insulin that controls blood sugar levels. This can lead to better regulation of blood sugar, better appetite control and reduced fat storage.*
Recently, berberine has soared in popularity, due to its “side effect” of promoting healthy weight loss via its actions on blood sugar and metabolism. Like the weight loss injections that have become popular recently, berberine increases levels of GLP-1, a key hormone that regulates fat-burning metabolism. But it works in a different way in the body.*
Instead of imitating GLP-1 as the synthetic injections do, berberine promotes natural GLP-1 secretion in the intestines. This is an incredibly important distinction! Unlike those injections, berberine has an excellent track record when it comes to safety, and it can improve your overall metabolic and digestive health while helping you lose weight.*
Berberine also helps reduce inflammation and promotes a healthy gut microbiome—two important factors in maintaining a healthy weight.*
Berberine’s weight loss benefits may also be related to its ability to increase metabolic rate and influence the activity of genes and enzymes involved in fat metabolism. In addition, some studies suggest that berberine may impact hormones involved in appetite regulation, including ghrelin, a hormone that stimulates hunger, and leptin, a hormone that signals satiety.*
Berberine has also been clinically validated to help lower total cholesterol, particularly the less favorable LDL type, and is effective in supporting healthy lipid levels. The patented berberine extract found in Durable BERBERINE was shown in a clinical trial to lower total cholesterol by 8% in just 60 days.*
For more targeted support for cholesterol balance, we recommend you try our Durable HEART formula, which can be taken together with Durable BERBERINE.*
Berbevis® Berberine Phytosome™ (1,100 mg)
Durable BERBERINE is made with Berbevis®, a patented, clinically studied, standardized phytosome-form berberine extract that is clinically proven to significantly reduce insulin resistance within just 30 days while reducing visceral fat by 22% on average within 60 days. Visceral fat, which surrounds your organs, is considered the most dangerous kind of fat.*
While typical berberine extracts are notoriously difficult for the body to absorb, Berbevis® Berberine Phytosome™ solves this problem with a next-generation phytosome delivery system that offers 10x better absorption compared to other berberine supplements.*
In a landmark 60-day study Berbevis®:
- Slashed fasting insulin levels by 42%*
- Reduced HOMA score (a measure of insulin resistance) by 49%*
- Decreased fasting blood sugar by 12%*
- Reduced visceral fat by 22%*
Greenselect® Green Tea Phytosome™ (300 mg)
Greenselect® is a patented, decaffeinated phytosome-form green tea extract shown in clinical trials to support weight loss of up to 30 pounds in 90 days when combined with a reduced calorie diet.*
Green tea polyphenols, particularly catechins such as epigallocatechin gallate (EGCG), have been extensively studied for their health benefits, including their role in supporting weight loss. Greenselect® Green Tea Phytosome™ combines green tea polyphenols with phospholipids in a phytosome delivery system to improve their absorption and bioavailability. Greenselect® offers a 2-fold increase in absorption and a 20% increase in plasma antioxidant potential compared to standard green tea extract.*
Greenselect® Green Tea Phytosome™ provides safe and extremely effective natural support for weight loss by stimulating thermogenesis (the process by which the body generates heat and energy from metabolism of food) and fat oxidation (the process of breaking down fat into energy). It also helps regulate appetite and promotes feelings of satiety, helping to prevent overeating.*
In one study, Greenselect® helped a group of men and women lose an average of 13.23 pounds in 45 days, and an average of 30.86 pounds in 90 days. This remarkable weight loss was accompanied with a 12% reduction in body mass index (BMI) after 90 days.*
Another clinical trial showed a 13.9% reduction in BMI, a 10.7% reduction in waistline for men, a 9.1% reduction in waistline for women and 7.1% reduction in fasting glucose all around.*
Albion® Chromium (200 mcg)
Durable BERBERINE features top-of-the-line Albion® chromium. This patented, chelated (amino acid-bound) form of chromium offers superior absorption, blood sugar balancing benefits and fat loss support.*
Chromium is an essential trace mineral that plays a crucial role in blood sugar metabolism, the body's ability to process and utilize sugar from the bloodstream for energy. It helps maintain blood sugar balance, which is a critical factor in reducing fat storage. Studies have shown that chromium can help increase lean body mass while decreasing body fat percentage.*
Chromium can also help fight cravings that can derail your weight loss plan. Some research suggests that chromium supplementation helps reduce cravings for carbohydrates and sweets by influencing neurotransmitters involved in appetite regulation.*
Why We Use Amber Glass Bottles vs. Clear Glass or Plastic
- Glass is infinitely recyclable and reusable.
- Protects the ingredients from UV light damage.
- No risk of chemicals in plastics leaching into pills.
Directions & Label Information
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For adults only. Take 1 capsule twice daily before or after your two biggest meals of the day, or as directed by your healthcare practitioner. For additional support, Dr. Passero recommends taking 1 additional capsule before or after a third meal.
Clean Formula Guarantee
Non-GMO | Gluten Free | Vegan | Dairy Free | Soy Free | Nut Free | Egg Free | Free of Artificial Colors or Preservatives
Timing of Results
Like most nutritional supplements, Durable BERBERINE will take time and consistent use in order to achieve maximum effectiveness. While individual results may vary, the clinical studies show the best results often begin around 60 days, with results that keep improving over time. Dr. Passero recommends taking Durable BERBERINE for at least 90 days before evaluating your progress so you can make a proper assessment.
Side Effects & Interactions
Since Durable BERBERINE is made with 100% natural ingredients, the vast majority of users have no side effects, allergic reactions or interactions. It has no known interactions with most prescription drugs, medications or other dietary supplements.
Long Term Use & When To Stop
Durable BERBERINE is safe to take on an ongoing basis. However, it is possible to switch to a maintenance dose of 1 capsule per day or to stop completely. This depends on various factors including your initial weight loss and/or blood sugar goals, genetics, diet and exercise routine.
For Those with Low Blood Sugar
If you plan to take Durable BERBERINE for weight loss support but already have normal or low blood sugar, you do not have to be concerned about this product lowering it further. The ingredients work specifically to promote blood sugar balance, so it will only have a blood sugar lowering effect if your levels are elevated.
Cautions
If taking medication, have a medical condition, or are pregnant or breastfeeding, consult your healthcare practitioner before use. Keep out of the reach of children.
Contents
Each bottle contains 60 vegetarian capsules (typically a 30 day supply).
Storage
Keep tightly closed in a cool, dry place.

Durable BERBERINE®
Weight Control & Blood Sugar Balance
Savings based on 1 bottle price

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★★★★★
The Results Speak For Themselves
"I've only taken this for about a month but I've
lost 5 pounds, a little more than 1 pound a week.
I'm happy with that. Slow and steady means I will
hopefully keep it off.”
— Clayton B.
What It Does
+
Berberine is an extraordinarily powerful plant alkaloid clinically proven to effectively promote blood sugar balance—and weight loss. Berberine naturally increases levels of GLP-1, a key hormone that regulates fat-burning metabolism. It also activates an enzyme called AMPK (often referred to as your “metabolic master switch”) to promote appetite control, reduced fat storage and blood sugar regulation, as well as balanced cholesterol.*
Widely considered the best berberine extract in the world, Berbevis® features a next-generation phytosome delivery system that gives it 10x better absorption than other forms of berberine.*
This cutting-edge formula also includes a 300 mg dose of Greenselect®, an advanced decaffeinated green tea extract that also leverages phytosome technology and has been proven to rev up your metabolism and support weight loss of up to 30 pounds in 90 days when combined with a reduced calorie diet. Greenselect® Green Tea Phytosome™ offers a 2-fold increase in absorption and a 20% increase in plasma antioxidant potential compared to standard green tea extract.*
Additionally, a therapeutic 200 mcg dose of premium-grade, highly absorbable Albion® chromium provides synergistic support for blood sugar balance. As an essential trace mineral, chromium plays an important role in helping the body process and utilize sugar from the bloodstream for energy, a critical factor in reducing fat storage. Research shows that chromium can help improve body composition while fighting cravings that can derail your weight loss efforts.*
No other berberine supplement on the market combines these effective ingredients into one convenient formula. Durable BERBERINE offers exceptional and comprehensive support for healthy weight management, blood sugar regulation, metabolic health and cholesterol balance with just two capsules a day, and without adverse side effects.*
This synergistic combination of powerful, clinically validated ingredients:*
- Can help you lose up to 30 pounds in 90 days
- Reduces hard-to-lose visceral fat by 22% in 60 days
- Reduces body mass index (BMI) by up to 13.9%
- Can help shrink your waistline by up to 10.7%
- Boosts GLP-1 levels to help increase fat-burning
- Helps suppress appetite and promotes satiety
- Reduces insulin resistance in as little as 30 days
- Reduces fasting insulin levels by 42% in 60 days
- Promotes metabolic health and blood sugar balance
- Supports healthy cholesterol and triglyceride levels
General Product Info:
- 60 vegetarian capsules (a 30 day supply)
- Made in the USA in an FDA inspected, cGMP facility
- Every batch is 3rd party tested for safety and purity
- Packaged in premium, non-toxic amber glass bottles
- One-year return policy with free return shipping
Why It Works
+
Dr. Passero’s 20+ years of experience went into formulating Durable BERBERINE, which features a potent 1,100 mg daily dose of a standardized, highly absorbable berberine extract called Berbevis® Berberine Phytosome™. Widely recognized as one of the best berberine extracts in the world, this phytosome-form extract utilizes an innovative delivery system to provide up to 10x better absorption than the berberine extracts found in most supplements.*
Berberine’s powerful weight loss promoting, metabolic boosting and blood sugar balancing effects are synergistically enhanced with 300 mg of clinically studied, caffeine-free Greenselect® Green Tea Phytosome™ and a therapeutic 200 mcg dose of Albion® chromium for even greater benefits.*
What Is Berberine and How Does It Work?
Berberine is an extraordinarily powerful plant alkaloid found in some of nature’s most revered medicinal herbs, including barberry, goldenseal and Oregon grape root. Extensive scientific research shows that, among a slew of health benefits, berberine excels at promoting blood sugar balance—and weight loss—via its regulating effects on metabolism.*
Berberine activates an energy-stabilizing enzyme called AMPK, often referred to as the “metabolic master switch,” which helps maintain balanced blood sugar levels and overall metabolic health. In addition, berberine enhances insulin sensitivity, which means it helps cells respond more effectively to the hormone insulin that controls blood sugar levels. This can lead to better regulation of blood sugar, better appetite control and reduced fat storage.*
Recently, berberine has soared in popularity, due to its “side effect” of promoting healthy weight loss via its actions on blood sugar and metabolism. Like the weight loss injections that have become popular recently, berberine increases levels of GLP-1, a key hormone that regulates fat-burning metabolism. But it works in a different way in the body.*
Instead of imitating GLP-1 as the synthetic injections do, berberine promotes natural GLP-1 secretion in the intestines. This is an incredibly important distinction! Unlike those injections, berberine has an excellent track record when it comes to safety, and it can improve your overall metabolic and digestive health while helping you lose weight.*
Berberine also helps reduce inflammation and promotes a healthy gut microbiome—two important factors in maintaining a healthy weight.*
Berberine’s weight loss benefits may also be related to its ability to increase metabolic rate and influence the activity of genes and enzymes involved in fat metabolism. In addition, some studies suggest that berberine may impact hormones involved in appetite regulation, including ghrelin, a hormone that stimulates hunger, and leptin, a hormone that signals satiety.*
Berberine has also been clinically validated to help lower total cholesterol, particularly the less favorable LDL type, and is effective in supporting healthy lipid levels. The patented berberine extract found in Durable BERBERINE was shown in a clinical trial to lower total cholesterol by 8% in just 60 days.*
For more targeted support for cholesterol balance, we recommend you try our Durable HEART formula, which can be taken together with Durable BERBERINE.*
Berbevis® Berberine Phytosome™ (1,100 mg)
Durable BERBERINE is made with Berbevis®, a patented, clinically studied, standardized phytosome-form berberine extract that is clinically proven to significantly reduce insulin resistance within just 30 days while reducing visceral fat by 22% on average within 60 days. Visceral fat, which surrounds your organs, is considered the most dangerous kind of fat.*
While typical berberine extracts are notoriously difficult for the body to absorb, Berbevis® Berberine Phytosome™ solves this problem with a next-generation phytosome delivery system that offers 10x better absorption compared to other berberine supplements.*
In a landmark 60-day study Berbevis®:
- Slashed fasting insulin levels by 42%*
- Reduced HOMA score (a measure of insulin resistance) by 49%*
- Decreased fasting blood sugar by 12%*
- Reduced visceral fat by 22%*
Greenselect® Green Tea Phytosome™ (300 mg)
Greenselect® is a patented, decaffeinated phytosome-form green tea extract shown in clinical trials to support weight loss of up to 30 pounds in 90 days when combined with a reduced calorie diet.*
Green tea polyphenols, particularly catechins such as epigallocatechin gallate (EGCG), have been extensively studied for their health benefits, including their role in supporting weight loss. Greenselect® Green Tea Phytosome™ combines green tea polyphenols with phospholipids in a phytosome delivery system to improve their absorption and bioavailability. Greenselect® offers a 2-fold increase in absorption and a 20% increase in plasma antioxidant potential compared to standard green tea extract.*
Greenselect® Green Tea Phytosome™ provides safe and extremely effective natural support for weight loss by stimulating thermogenesis (the process by which the body generates heat and energy from metabolism of food) and fat oxidation (the process of breaking down fat into energy). It also helps regulate appetite and promotes feelings of satiety, helping to prevent overeating.*
In one study, Greenselect® helped a group of men and women lose an average of 13.23 pounds in 45 days, and an average of 30.86 pounds in 90 days. This remarkable weight loss was accompanied with a 12% reduction in body mass index (BMI) after 90 days.*
Another clinical trial showed a 13.9% reduction in BMI, a 10.7% reduction in waistline for men, a 9.1% reduction in waistline for women and 7.1% reduction in fasting glucose all around.*
Albion® Chromium (200 mcg)
Durable BERBERINE features top-of-the-line Albion® chromium. This patented, chelated (amino acid-bound) form of chromium offers superior absorption, blood sugar balancing benefits and fat loss support.*
Chromium is an essential trace mineral that plays a crucial role in blood sugar metabolism, the body's ability to process and utilize sugar from the bloodstream for energy. It helps maintain blood sugar balance, which is a critical factor in reducing fat storage. Studies have shown that chromium can help increase lean body mass while decreasing body fat percentage.*
Chromium can also help fight cravings that can derail your weight loss plan. Some research suggests that chromium supplementation helps reduce cravings for carbohydrates and sweets by influencing neurotransmitters involved in appetite regulation.*
Why We Use Amber Glass Bottles vs. Clear Glass or Plastic
- Glass is infinitely recyclable and reusable.
- Protects the ingredients from UV light damage.
- No risk of chemicals in plastics leaching into pills.
Directions & Label Information
+
For adults only. Take 1 capsule twice daily before or after your two biggest meals of the day, or as directed by your healthcare practitioner. For additional support, Dr. Passero recommends taking 1 additional capsule before or after a third meal.
Clean Formula Guarantee
Non-GMO | Gluten Free | Vegan | Dairy Free | Soy Free | Nut Free | Egg Free | Free of Artificial Colors or Preservatives
Timing of Results
Like most nutritional supplements, Durable BERBERINE will take time and consistent use in order to achieve maximum effectiveness. While individual results may vary, the clinical studies show the best results often begin around 60 days, with results that keep improving over time. Dr. Passero recommends taking Durable BERBERINE for at least 90 days before evaluating your progress so you can make a proper assessment.
Side Effects & Interactions
Since Durable BERBERINE is made with 100% natural ingredients, the vast majority of users have no side effects, allergic reactions or interactions. It has no known interactions with most prescription drugs, medications or other dietary supplements.
Long Term Use & When To Stop
Durable BERBERINE is safe to take on an ongoing basis. However, it is possible to switch to a maintenance dose of 1 capsule per day or to stop completely. This depends on various factors including your initial weight loss and/or blood sugar goals, genetics, diet and exercise routine.
For Those with Low Blood Sugar
If you plan to take Durable BERBERINE for weight loss support but already have normal or low blood sugar, you do not have to be concerned about this product lowering it further. The ingredients work specifically to promote blood sugar balance, so it will only have a blood sugar lowering effect if your levels are elevated.
Cautions
If taking medication, have a medical condition, or are pregnant or breastfeeding, consult your healthcare practitioner before use. Keep out of the reach of children.
Contents
Each bottle contains 60 vegetarian capsules (typically a 30 day supply).
Storage
Keep tightly closed in a cool, dry place.









Unparalleled Natural Weight Loss & Blood Sugar Support
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Berbevis® Berberine Phytosome™
This clinically validated berberine extract provides 10x better absorption than typical berberine and has been shown to reduce visceral fat by 22% in 60 days.*
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Greenselect® Green Tea
This patented, decaffeinated green tea extract is proven to support weight loss of up to 30 pounds in 90 days when combined with a reduced calorie diet.*
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Albion® Chromium
An absorbable chelated form of the essential trace mineral chromium, which plays an important role in promoting balanced blood sugar, fat loss and controlling cravings.*
The Doctor Behind The Formula

Dr. Kevin Passero
Functional Medicine Expert, Licensed Naturopathic Physician and Durable Co-Founder
Durable BERBERINE is formulated with a unique, synergistic combination of berberine extract, green tea extract and chromium that I have used in my clinics for years with great success to help my patients lose weight, balance blood sugar and optimize metabolic activity. I'm truly excited about this effective new formula!

I was concerned about side effects I was having. I tried this product and went for lab work three months after and was very happy with the results.
I have been taking this product for 2 months. I have noticed I'm less hungry, I eat less and my clothes are fitting better. I'm down 5 lbs and can't wait to see the continued results. I have tried many products that were more expensive and less effective. I will be purchasing this again. I Love this company and the fact that the products are created by a Physician is a big plus in my book.
I have read many positive things about berberine and its support for weight loss, which influenced my decision to start taking the supplement. After careful consideration, I chose to use a particular product and have been very pleased with my experience. I have not experienced any side effects, such as stomach cramping or other issues. In fact, I have successfully lost over 20 pounds in the last five months. Additionally, I have noticed a significant decrease in my visceral fat, and my waist size has gone down from 38/40 inches to 34 inches. Throughout this journey, my energy levels have stayed high, and I have experienced a reduction in brain fog. Overall, I would highly recommend these products to anyone looking to support their weight loss journey.
I've been taking HEART & BERBERINE for almost two months. I'm feeling great! My weight is down 4 lbs. I'm looking forward to my next round of labs to see if my cholesterol numbers have dropped. I'm going to also add the Red Yeast to my regimen. Thank you Durable!!
Had my yearly physical and my glucose level was at 85. It dropped several points and this was my only change.