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What It Does

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Emerging research is showing that maintaining balance in your gut microbiome is key to maintaining optimal cardiovascular health, and specific probiotic strains can help promote that balance. Dr. Passero formulated Durable PROBIOTIC with this in mind, combining five of the most extensively studied, patented and genetically verified strains proven to provide cardiovascular health benefits beyond what typical probiotics provide, along with powerful support for digestive and immune health. In fact, our formula is one of the only probiotic supplements on the market made with a unique blend of strains proven to lower total cholesterol and boost HDL*

This synergistic blend of genetically verified probiotic strains:
• Helps to quickly balance your gut microbiome*
• Provides targeted support for cardiovascular health via the gut-heart axis*
• Contains a specific blend of strains proven to lower total cholesterol and boost HDL*
• Supports digestive regularity while reducing bloating and gas*
• Boosts immune and respiratory function so you stay healthy and strong*

General Product Info:
• 60 vegetarian capsules (a 30 day supply)
• No refrigeration required. Potency guaranteed through expiration
• Made in the USA in an FDA inspected, cGMP facility
• Every batch is 3rd party tested for safety and purity
• Packaged in sustainable, 100% non-toxic amber glass bottles
• One-year, any reason return policy with free return shipping

Why It Works

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When you think of probiotics, you probably think of digestive or immune health, which probiotics support via their ability to promote balance in your gut microbiome, the collection of microbes that inhabit your gut and influence your overall health in a multitude of ways.*

As scientists continue study these microbes and the metabolites they produce in the body, we’re learning that they influence everything from digestion and immune function to mood and metabolism, and even heart health via what is known as the gut-heart axis.*

The term “gut-heart axis” simply describes the relationship between gut health and cardiovascular function, and it has become the focus of an emerging area of research. Much of this research is revealing that gut microbiome balance plays a critical role in your overall cardiovascular wellness and that certain probiotic strains can provide targeted support for cholesterol balance, normal blood pressure, a normal inflammatory response and healthy metabolic function.*

Dr. Passero formulated Durable PROBIOTIC with a precise blend of patented, genetically verified probiotic strains shown in clinical research to provide impressive cardiovascular benefits—including support for healthy cholesterol balance—as well as powerful support for digestive, immune and respiratory health.*

Why We Need Probiotics More Than Ever
Ongoing studies on the human gut microbiome shows that beneficial microbes are rapidly being depleted from our bodies, and the consequences for our health could be devastating. Factors like overuse of antibiotics, excessive sanitization, modern farming practices that damage natural ecosystems, and diets high in ultra-processed, refined foods are destroying the microbial balance and healthy diversity of our collective microbiome.*

Common digestive issues like bloating, gas and indigestion can all stem from an imbalance of your gut microbiome, but they’re just the tip of the iceberg. Gut health issues can lead to poor nutrient absorption, increased inflammation, lowered immune health, mood swings, fatigue and suboptimal cardiovascular wellness.*

The solution? Supplementing with probiotics—live bacteria that colonize in your gut and help to bring your vital microbiome back into balance. But it is essential to get the right strains of healthy bacteria, and in the right amounts.*

The Right Strains in the Right Amounts—Guaranteed
Durable PROBIOTIC features a precise blend of five patented, genetically verified probiotic strains cultivated in FDA-inspected US labs and have been proven in human clinical trials to provide significant cardiovascular, digestive and immune health benefits:*

Bifidobacterium lactis HN019™
Bifidobacterium lactis Bl-04®
Lactobacillius acidophilus NCFM®
Lactobacillius rhamnosus HN001™
Lactobacillus paracasei LPC-37®

Each of these strains is genetically verified by independent lab testing so you know you’re getting clinically studied and proven effective probiotics—and all the benefits they’ve been proven to provide.*

Many probiotics contain far more probiotic cultures than what the research shows is effective. But more isn’t always better. That’s why Durable PROBIOTIC contains the clinically proven effective amounts (a total of 10 billion CFU) of five key patented strains that have been shown to deliver powerful, measurable benefits.*

Durable PROBIOTIC is carefully manufactured to guarantee that the live cultures inside will remain viable and at the full potencies listed on the label without the need for refrigeration. That way you can be sure you’re getting the amounts of beneficial bacteria shown in the research to provide the benefits you want.*

When It Comes to Probiotics, Few Things Are More Important Than Genetic Verification
Genetic verification is a process that ensures that the bacterial strains found in your probiotic have been positively identified based on the composition of their DNA.*

Many products contain the common probiotic Lactobacillus acidophilus. Lactobacillus is the genus, and acidophilus is the species. Each probiotic species has a vast amount of genetic variation, and each variation is referred to as a strain. So even though the labels might all say Lactobacillus acidophilus, the actual strains found inside might not be the same. (Genetically verified strains are typically identified on a label with a sequence of numbers and/or letters listed after the probiotic species. For example, Lactobacillus acidophilus NCFM, or Bifidobacterium lactis HN019.)*

If your probiotic is not genetically verified down to the level of the strain, you really have no idea what you are getting or the effects it might have on your body. DNA verification ensures that what is stated on the bottle is in fact what you are taking. Furthermore, strain-based probiotics are the only ones with human clinical trials and research backing the beneficial effects. That’s why Dr. Passero formulated Durable PROBIOTIC with five of the most well researched, genetically verified probiotic strains available.*

Why Durable PROBIOTIC Is Your Best Choice
When it comes to probiotic supplements, your options are nearly endless. So what makes Durable PROBOTIC your best choice? Here are 5 reasons:*

1. Durable PROBIOTIC is formulated with a synergistic blend of patented, genetically verified strains cultivated in FDA inspected labs in the US.*
2. It’s one of the ONLY probiotic supplement specifically formulated to provide cardiovascular benefits in addition to digestive and immune system support.*
3. It features a specific blend of strains proven to lower total cholesterol and boost HDL.*
4. Just one small capsule per day provides extraordinary health benefits.*
5. No refrigeration is required and potency is guaranteed through expiration.*

Why We Use Amber Glass Bottles vs. Clear Glass or Plastic:
• Sustainability: Glass is infinitely recyclable and reusable.
• UV Protection: Amber glass protects the ingredients from light damage.
• 100% Non-Toxic: No risk of chemicals found in plastics leaching into the pills.

Directions & Label Information

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Directions
For adults only. Take one capsule once daily or as directed by your healthcare practitioner. For additional support, Dr. Passero typically recommends up to 2 capsules per day.

Contents
Each bottle contains 30 vegetarian capsules (typically a 30 day supply).

Caution
If taking medication, pregnant or breastfeeding consult your healthcare practitioner before use. Keep out of the reach of children.

Storage
For best results, keep tightly closed and store in a cool dry place or keep refrigerated (refrigeration not required).

• Non-GMO • Gluten Free • Vegan • Dairy Free • Soy Free • Nut Free • Egg Free • No Artificial Colors or Preservatives


Questions? Click Here to Read Our FAQ


NEW & IMPROVED

Durable PROBIOTIC® - Subscription

Advanced, Multi-Strain Support for Heart, Gut & Immune Health


Made with patented, genetically verified strains clinically proven to promote heart health, Durable PROBIOTIC will help balance your gut microbiome, and in the process, support your cardiovascular, digestive and immune systems—all in just one capsule per day. No refrigeration required.*

Savings based on 1 bottle price

What It Does

+
Emerging research is showing that maintaining balance in your gut microbiome is key to maintaining optimal cardiovascular health, and specific probiotic strains can help promote that balance. Dr. Passero formulated Durable PROBIOTIC with this in mind, combining five of the most extensively studied, patented and genetically verified strains proven to provide cardiovascular health benefits beyond what typical probiotics provide, along with powerful support for digestive and immune health. In fact, our formula is one of the only probiotic supplements on the market made with a unique blend of strains proven to lower total cholesterol and boost HDL*

This synergistic blend of genetically verified probiotic strains:
• Helps to quickly balance your gut microbiome*
• Provides targeted support for cardiovascular health via the gut-heart axis*
• Contains a specific blend of strains proven to lower total cholesterol and boost HDL*
• Supports digestive regularity while reducing bloating and gas*
• Boosts immune and respiratory function so you stay healthy and strong*

General Product Info:
• 60 vegetarian capsules (a 30 day supply)
• No refrigeration required. Potency guaranteed through expiration
• Made in the USA in an FDA inspected, cGMP facility
• Every batch is 3rd party tested for safety and purity
• Packaged in sustainable, 100% non-toxic amber glass bottles
• One-year, any reason return policy with free return shipping

Why It Works

+
When you think of probiotics, you probably think of digestive or immune health, which probiotics support via their ability to promote balance in your gut microbiome, the collection of microbes that inhabit your gut and influence your overall health in a multitude of ways.*

As scientists continue study these microbes and the metabolites they produce in the body, we’re learning that they influence everything from digestion and immune function to mood and metabolism, and even heart health via what is known as the gut-heart axis.*

The term “gut-heart axis” simply describes the relationship between gut health and cardiovascular function, and it has become the focus of an emerging area of research. Much of this research is revealing that gut microbiome balance plays a critical role in your overall cardiovascular wellness and that certain probiotic strains can provide targeted support for cholesterol balance, normal blood pressure, a normal inflammatory response and healthy metabolic function.*

Dr. Passero formulated Durable PROBIOTIC with a precise blend of patented, genetically verified probiotic strains shown in clinical research to provide impressive cardiovascular benefits—including support for healthy cholesterol balance—as well as powerful support for digestive, immune and respiratory health.*

Why We Need Probiotics More Than Ever
Ongoing studies on the human gut microbiome shows that beneficial microbes are rapidly being depleted from our bodies, and the consequences for our health could be devastating. Factors like overuse of antibiotics, excessive sanitization, modern farming practices that damage natural ecosystems, and diets high in ultra-processed, refined foods are destroying the microbial balance and healthy diversity of our collective microbiome.*

Common digestive issues like bloating, gas and indigestion can all stem from an imbalance of your gut microbiome, but they’re just the tip of the iceberg. Gut health issues can lead to poor nutrient absorption, increased inflammation, lowered immune health, mood swings, fatigue and suboptimal cardiovascular wellness.*

The solution? Supplementing with probiotics—live bacteria that colonize in your gut and help to bring your vital microbiome back into balance. But it is essential to get the right strains of healthy bacteria, and in the right amounts.*

The Right Strains in the Right Amounts—Guaranteed
Durable PROBIOTIC features a precise blend of five patented, genetically verified probiotic strains cultivated in FDA-inspected US labs and have been proven in human clinical trials to provide significant cardiovascular, digestive and immune health benefits:*

Bifidobacterium lactis HN019™
Bifidobacterium lactis Bl-04®
Lactobacillius acidophilus NCFM®
Lactobacillius rhamnosus HN001™
Lactobacillus paracasei LPC-37®

Each of these strains is genetically verified by independent lab testing so you know you’re getting clinically studied and proven effective probiotics—and all the benefits they’ve been proven to provide.*

Many probiotics contain far more probiotic cultures than what the research shows is effective. But more isn’t always better. That’s why Durable PROBIOTIC contains the clinically proven effective amounts (a total of 10 billion CFU) of five key patented strains that have been shown to deliver powerful, measurable benefits.*

Durable PROBIOTIC is carefully manufactured to guarantee that the live cultures inside will remain viable and at the full potencies listed on the label without the need for refrigeration. That way you can be sure you’re getting the amounts of beneficial bacteria shown in the research to provide the benefits you want.*

When It Comes to Probiotics, Few Things Are More Important Than Genetic Verification
Genetic verification is a process that ensures that the bacterial strains found in your probiotic have been positively identified based on the composition of their DNA.*

Many products contain the common probiotic Lactobacillus acidophilus. Lactobacillus is the genus, and acidophilus is the species. Each probiotic species has a vast amount of genetic variation, and each variation is referred to as a strain. So even though the labels might all say Lactobacillus acidophilus, the actual strains found inside might not be the same. (Genetically verified strains are typically identified on a label with a sequence of numbers and/or letters listed after the probiotic species. For example, Lactobacillus acidophilus NCFM, or Bifidobacterium lactis HN019.)*

If your probiotic is not genetically verified down to the level of the strain, you really have no idea what you are getting or the effects it might have on your body. DNA verification ensures that what is stated on the bottle is in fact what you are taking. Furthermore, strain-based probiotics are the only ones with human clinical trials and research backing the beneficial effects. That’s why Dr. Passero formulated Durable PROBIOTIC with five of the most well researched, genetically verified probiotic strains available.*

Why Durable PROBIOTIC Is Your Best Choice
When it comes to probiotic supplements, your options are nearly endless. So what makes Durable PROBOTIC your best choice? Here are 5 reasons:*

1. Durable PROBIOTIC is formulated with a synergistic blend of patented, genetically verified strains cultivated in FDA inspected labs in the US.*
2. It’s one of the ONLY probiotic supplement specifically formulated to provide cardiovascular benefits in addition to digestive and immune system support.*
3. It features a specific blend of strains proven to lower total cholesterol and boost HDL.*
4. Just one small capsule per day provides extraordinary health benefits.*
5. No refrigeration is required and potency is guaranteed through expiration.*

Why We Use Amber Glass Bottles vs. Clear Glass or Plastic:
• Sustainability: Glass is infinitely recyclable and reusable.
• UV Protection: Amber glass protects the ingredients from light damage.
• 100% Non-Toxic: No risk of chemicals found in plastics leaching into the pills.

Directions & Label Information

+
Directions
For adults only. Take one capsule once daily or as directed by your healthcare practitioner. For additional support, Dr. Passero typically recommends up to 2 capsules per day.

Contents
Each bottle contains 30 vegetarian capsules (typically a 30 day supply).

Caution
If taking medication, pregnant or breastfeeding consult your healthcare practitioner before use. Keep out of the reach of children.

Storage
For best results, keep tightly closed and store in a cool dry place or keep refrigerated (refrigeration not required).

• Non-GMO • Gluten Free • Vegan • Dairy Free • Soy Free • Nut Free • Egg Free • No Artificial Colors or Preservatives


Questions? Click Here to Read Our FAQ


Cultivate Lasting Health With Proven Probiotic Strains

Durable PROBIOTIC is made with a blend of two patented and extensively researched, genetically verified bacterial strains that have been proven in human clinical trials to ease digestive discomfort while boosting immune health.*
  • Cardio Support Blend

    Cardio Support Blend

    L. paracasei LPC-37®, L. rhamnosus HN001™, L. acidophilus NCFM® and B. lactis HN019™, strains known for their gut health benefits, significantly lowered total cholesterol while raising “good” HDL within 8 weeks in gold-standard clinical trial.*

  • Gut Health Support Blend

    Gut Health Support Blend

    L. acidophilus NCFM® has been validated in over 45 human trials and shown to significantly reduce gas, bloating and abdominal discomfort while improving regularity. B. lactis HN019™ is shown to significantly enhance gut motility and regularity.*

  • Immune Support Blend

    Immune Support Blend

    B. lactis Bl-04® is proven to increase upper respiratory resistance while supporting the body’s natural immune defenses in the nose. B. lactis HN019™ has been shown to significantly enhance immune function in individuals over the age of 55.*

The Doctor Behind The Formula

Dr. Kevin Paserro Answers Your Questions

How is gut health connected to heart health?

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Researchers now understand that the health of your gut is linked to the health of the rest of your body, including your central nervous system and cardiovascular system. The relationship between your digestive system and your cardiovascular system is known as the gut-heart axis.*

While much of the recent research on the impact of microbiome balance on health has focused on the gut-brain connection, emerging research is beginning to show a link between the gut health and heart health. These studies have mainly focused on metabolites the gut microbiota produce as a byproduct of breaking down the food you eat into nutrients. Your diet—and the composition of your gut microbiome—determines which metabolites, and how many of them, are produced. Studies have linked higher levels of certain metabolites to the development of cardiovascular issues.*

One metabolite known as trimethylamine (TMA) is produced when your gut microbes feed on choline, a nutrient found in eggs, red meat, poultry and fish. The metabolite TMA gets converted to trimethylamine N-oxide (TMAO) in your liver. TMAO has been linked with gut microbiome imbalances, and researchers are examining its connection to arterial plaque and cardiovascular risk.*

Additionally, imbalances in the gut microbiome have been linked to higher levels of inflammation, which is known to play a role in heart health.*


Why is genetic verification of probiotic strains important?

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Many people don't realize that genetic verification is one of the most important features to look for in a probiotic supplement.

The bacterial strains in probiotic supplements must be genetically identified and verified via testing to confirm that they are the ones stated on the label. This eliminates the possibility of contamination with undesirable microbes and ensures that you’re getting the specific strains tied to the research that has demonstrated specific health benefits. These strains are designated with names, letters and numbers. For example: Bifidobacterium lactis Bl-04®. With over 200 different bifidobacterial strains out there in the world, getting the right one is important.*

Durable PROBIOTIC’s patented strains have been genetically verified, so you know exactly what you’re getting in each capsule.*


Does Durable PROBIOTIC need to be refrigerated?

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No refrigeration necessary! Durable PROBIOTIC is carefully manufactured, stored and shipped to make sure that the live bacteria it contains are protected. This formula is guaranteed to retain its full potency until the expiration date printed on the bottle. Like all supplements, we recommend storing your probiotics in a cool, dry place out of direct sunlight.*


How long will it take to feel the effects?

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With continuous daily use, you can expect to see noticeable improvements in digestive regularity and comfort within 2-4 weeks. A blend of four of the strains in Durable PROBIOTIC were shown to improve total and HDL cholesterol balance within 8 weeks.*


What’s the best time to take Durable PROBIOTIC?

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While you can take Durable PROBIOTIC any time of day and with or without food, taking it on an empty stomach (15-30 minutes before eating or 2-3 hours after a meal) is ideal. For most of us, that means taking it first thing in the morning and/or before bed at night.*


Can I take more than the recommended dose?

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You can take up to two capsules daily for additional digestive, immune and cardiovascular health support.*


Are there any side effects?

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Studies have not shown any significant known side effects associated with taking the strains found in Durable PROBIOTIC. However, as your digestive system adjusts and rebalances, you might experience some minor, short-term digestive discomfort.*

Pregnant and nursing women should consult with their healthcare provider prior to any use. If you have any medical conditions or are taking any type of medication, it’s always best to check with your healthcare provider before taking any supplements.*


Are there any other Durable products I should consider when it comes to supporting my heart and cardiovascular health?

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Our bestselling Durable HEART® formula offers clinically proven natural support for healthy cholesterol levels, while Durable BLOOD PRESSURE® helps balance blood pressure naturally.*

Research shows that magnesium is an essential nutrient for cardiovascular health, so you might want to consider adding Durable MAGNESIUM® to your regimen for extra support.*

In addition, our Durable CoQ10® formula provides an extra-strength dose of this critical cardiovascular nutrient in an industry-leading, crystal-free form, delivered as a softgel for maximum absorption.*

If you have severe or stubborn cholesterol issues, including genetically high cholesterol, consider Durable HEART PLUS®. This money-saving bundle combines Durable HEART with Durable RED YEAST RICE. You can save up to $30 per 1-month supply vs. buying 1 bottle of each product separately. Since these two formulas help lower dangerous LDL cholesterol via different mechanisms of action, combining them can produce remarkable and comprehensive results.*


What is the Nuflow Complex that is listed in your Other Ingredients?

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Nuflow is a natural filler and flowing agent made from the outer hulls of rice. Flowing agents are used in the production of all encapsulated or tableted supplements to help prevent the ingredients from clumping as they flow through the encapsulating machinery. Most companies use synthetic flowing agents like silicon dioxide, magnesium stearate, talc or steric acid, which can potentially inhibit the absorption of the active ingredients or may be potentially harmful.*


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