Note: Durable PROBIOTIC is now new and improved with expanded digestive health benefits! This enhanced formula features a 40% increase in probiotic strains and a 120% increase in CFUs. It now includes seven diverse, patented and genetically verified strains supported by 427 human clinical studies. We've also added artichoke extract—a potent natural prebiotic and digestive aid that promotes bile flow, effectively reduces reflux symptoms and improves fat digestion.*

Drawing on over 20 years of clinical experience, Dr. Passero formulated Durable PROBIOTIC to help rapidly rebalance your microbiome and relieve a wide range of digestive issues—while improving virtually every aspect of your overall health.*

Bringing together seven of the most extensively researched, genetically verified probiotic strains, Durable PROBIOTIC delivers a powerful 22 billion CFU in every capsule. These patented strains have been shown in 427 human clinical trials to restore gut balance, promote optimal digestion, boost immune function and even lower cholesterol.*

While typical probiotics only address colon health, Durable PROBIOTIC provides full-spectrum digestive support. Remarkably, Durable PROBIOTIC’s clinically backed strains have been shown to improve overall digestive health in 85% of people within 30 days, while significantly reducing bloating, gas, constipation and abdominal discomfort.*

Unlike many formulas that rely on untested, generic strains or inflate their CFU count with unproven “fluff,” Durable PROBIOTIC uses genetically verified strains that have been cultivated in FDA-inspected U.S. labs, so you know you’re getting premium, clinically studied strains that have been proven to deliver real, measurable benefits. Plus, every strain is acid-resistant and shelf-stable—no refrigeration required—so you can be sure your probiotics will reach your intestines alive and active, where they can go to work fast.*

What truly makes Durable PROBIOTIC unique is the inclusion of standardized artichoke extract—a potent botanical prebiotic and digestive aid. This clinically studied extract promotes bile flow, supports fat digestion and has been proven to reduce reflux symptoms by 40% while cutting upper abdominal discomfort and nausea in half—benefits you won’t find in most probiotics.*

Whether you want to address stubborn digestive symptoms, boost your immune resilience, or simply rebalance your microbiome for better overall health, you won’t find a more effective, clinically validated probiotic for comprehensive gut and overall health.*

This synergistic blend of clinically proven ingredients:*

• Improves overall digestive health in up to 85% of people
• Reduces bloating and gas while improving regularity
• Reduces reflux symptoms by up to 40% and improves upper GI comfort
• Relieves abdominal discomfort and nausea
• Promotes bile flow and improves fat digestion
• Reduces intestinal inflammation and permeability (“leaky gut”)
• Boosts natural killer (NK) cell activity for enhanced immune function
• Promotes optimal respiratory resistance
• Lowers cholesterol and boosts HDL in just 8 weeks
• Quickly balances your gut microbiome for optimal overall health

General Product Info:

• 30 vegetarian capsules (a 30 day supply)
• No refrigeration required – potency guaranteed through expiration
• Made in the USA in an FDA inspected, cGMP facility
• Every batch is 3rd party tested for safety and purity
• Packaged in premium, non-toxic amber glass bottles
• One-year return policy with free return shipping

When most people think of probiotics, they think of digestion—and for good reason. Probiotics help maintain a healthy balance in the gut microbiome, the diverse ecosystem of bacteria that live in your digestive tract and play a vital role in your overall health. But recent research has made one thing clear: Not all probiotics are created equal—and not all digestive symptoms originate from the same part of the digestive system.*

That’s why Durable PROBIOTIC was formulated to work across your entire digestive system—from your stomach and small intestine to your colon—delivering fast, effective relief and long-term microbiome support.*

It starts with your gut microbiome, which influences not only digestion, but immune function, metabolism, mood and even cardiovascular function via the gut-heart axis—the complex connection between gut health and heart health. When this delicate microbial ecosystem becomes imbalanced due to stress, illness, antibiotics, processed foods or environmental toxins, the result can be bloating, gas, constipation, irregularity and increased inflammation throughout the body.*

Durable PROBIOTIC works to restore balance by delivering seven clinically validated probiotic strains, each genetically verified to ensure potency and consistency. These strains have been studied in 427 human clinical trials and shown to:*

• Promote regularity and relieve bloating and gas
• Help your body eliminate waste more efficiently
• Reduce intestinal inflammation and permeability
• Increase the presence of beneficial bifidobacteria, which decline with age
• Enhance immune cell activity, especially in adults over 55
• Lower cholesterol and boost beneficial HDL

Impressively, the strains in Durable PROBIOTIC were shown to improve overall digestive health in 85% of people within 30 days, while significantly reducing bloating in 78% of people, easing constipation in 74% of people and relieving abdominal discomfort in 80% of people.*

A key element that makes Durable PROBIOTIC unique is the addition of standardized artichoke extract, an often overlooked but essential digestive aid. Artichoke is rich in chlorogenic acids and compounds that promote healthy bile flow, improve fat digestion and deliver natural prebiotic support for gut flora. It’s also one of the few ingredients proven in clinical trials to relieve upper GI symptoms like reflux, burning, bloating and nausea — issues that typical probiotics don’t address.*

So while most probiotics only focus on colon health, Durable PROBIOTIC provides full-spectrum digestive support, easing discomfort from top to bottom—while simultaneously boosting immune resilience, lowering cholesterol and supporting heart health via the microbiome.*

It’s this comprehensive, scientifically grounded approach that makes Durable PROBIOTIC different. Whether you're looking to feel lighter and more comfortable every day, reduce disruptive digestive symptoms, or build a healthier foundation for long-term wellness, it all starts with your gut, and Durable PROBIOTIC is designed to help you take care of it.*

Clinically Proven, Genetically Verified Probiotic Strains
Durable PROBIOTIC contains 22 billion CFU across seven diverse, acid-resistant strains—each cultivated in FDA-inspected U.S. labs and verified by DNA sequencing for identity, potency and effectiveness.

These aren’t generic strains—they’re patented, clinically validated and genetically verified, which means you’re getting these exact bacteria shown in studies to work in real people:*

• Lactobacillus rhamnosus HN001™ – Promotes healthy digestion, supports immune health and contributes to cholesterol balance


• Lactobacillus acidophilus NCFM® – One of the most studied probiotic strains for digestive health, with hundreds of published studies demonstrating reduced gas, bloating and improved regularity


• Lactobacillus paracasei LPC-37® – Supports digestive comfort and microbial balance while contributing to immune function


• Bifidobacterium lactis Bi-07™ – Known for enhancing digestive regularity and gut health, especially in combination with NCFM®


• Bifidobacterium lactis Bl-04® – The most clinically studied Bifidobacterium strain, shown to bolster upper respiratory resistance while supporting the body’s natural immune defenses in the nose


• Bifidobacterium lactis HN019™ – Clinically shown to improve waste elimination, support digestive comfort and bolster immune function, especially in people over 55


• Bifidobacterium lactis DSM 15954 – Delivers additional microbiome support and contributes to a diverse and balanced gut environment

These strains were selected not just for their individual benefits, but for their synergistic effect when used together—especially in relieving symptoms like bloating, gas and irregularity, while also promoting immune strength and providing cardiovascular support.*

Artichoke Extract: A Rare but Powerful Digestive Ally
Most probiotic formulas stop at providing beneficial bacteria. Durable PROBIOTIC goes further by including 320 mg of standardized artichoke extract, an advanced botanical ingredient clinically proven to relieve upper GI symptoms and enhance fat digestion through healthy bile flow.*

In an 8-week study, artichoke extract was shown to:*

• Ease reflux symptoms by 40%
• Reduce upper abdominal burning by 50%
• Decrease bloating by 37%
• Cut nausea by 53%

It also acts as a natural prebiotic, helping to nourish and support the growth of beneficial gut bacteria—giving Durable PROBIOTIC an edge over standard probiotics that lack this essential microbiome support. Unlike the isolated prebiotics like inulin or fructooligosaccharides (FOS) found in some probiotic formula, which can actually increase bloating and gas in some people, artichoke soothes digestion and enhances abdominal comfort.*

No Overhyped CFUs, Just Proven Results
Many probiotic brands pack their formulas with inflated CFU counts and untested strains. But Durable PROBIOTIC uses only clinically effective doses of research-backed strains—no fillers, no guesswork, no fluff. Just ingredients that have stood the test of time and clinical validation.*

Why Durable PROBIOTIC Is Your Best Choice
When it comes to choosing a probiotic, there’s no shortage of options. But none match the clinical credibility, comprehensive support and precision formulation of Durable PROBIOTIC. Here are five reasons why it stands above the rest:*

1. Relieves Digestive Symptoms—Fast
Durable PROBIOTIC is clinically formulated to relieve the most common digestive complaints—including bloating, gas, constipation, irregularity, and even upper GI discomfort like reflux and nausea. Thanks to its unique combination of clinically validated probiotic strains and artichoke extract, many users report noticeable relief in as little as two weeks.*

2. Backed by 427 Human Clinical Trials
Every strain in Durable PROBIOTIC is supported by robust human clinical research—427 trials in total—making it one of the most scientifically validated probiotic supplements available anywhere. This includes the multi-strain GI blend clinically shown to improve overall digestive health in 85% of users within 30 days.*

3. Features 7 Genetically Verified, Patented Strains
Each strain in Durable PROBIOTIC is genetically verified and cultivated in FDA-inspected U.S. labs to ensure identity, safety and effectiveness. Unlike generic strains found in mass-market formulas, these are the exact strains used in clinical studies.*

4. Includes Artichoke Extract for Upper GI Symptom Relief
Durable PROBIOTIC is one of the only probiotics on the market to include standardized artichoke extract. This clinically proven, plant-based ingredient promotes bile flow, improves fat digestion and relieves upper GI symptoms like reflux, burning and nausea. It also acts as a natural prebiotic, enhancing the effectiveness of the probiotic strains by supporting a healthier microbial environment.*

5. Acid-Resistant and Shelf-Stable—No Refrigeration Needed
All strains in Durable PROBIOTIC are carefully selected and tested for their ability to survive stomach acid and bile salts, ensuring they reach your intestines alive and ready to work. The formula is fully shelf-stable, so there’s no need for refrigeration—and potency is guaranteed through expiration.*

If you're looking for a probiotic that goes beyond the basics to deliver real, measurable relief—from bloating and irregularity to reflux and gut discomfort—Durable PROBIOTIC delivers.*

Why We Use Amber Glass Bottles vs. Clear Glass or Plastic:

• Glass is infinitely recyclable and reusable.
• Protects the ingredients from UV light damage.
• No risk of chemicals leaching into the pills.

Directions
For adults only. Take 1 capsule once daily or as directed by your healthcare practitioner. While you can take Durable PROBIOTIC any time of the day with or without food, taking it on an empty stomach (15-30 minutes before eating or 2-3 hours after a meal) is ideal. For additional support, Dr. Passero recommends up to 2 capsules per day.

Clean Formula Guarantee
Non-GMO | Gluten Free | Vegan | Dairy Free | Soy Free | Nut Free | Egg Free | Free of Artificial Colors or Preservatives

Timing of Results
Like most nutritional supplements, Durable PROBIOTIC will take time and consistent use to build up in your system in order to achieve maximum effectiveness. With continuous daily use, you can expect to feel noticeable improvements to your digestive health within 2-4 weeks, with results improving over time.

Side Effects & Interactions
Since Durable PROBIOTIC is made with 100% natural ingredients, the vast majority of users have no side effects, allergic reactions or interactions. It has no known interactions with most prescription drugs, medications or other dietary supplements.

Caution
If taking medication, pregnant or breastfeeding, consult your healthcare practitioner before use. Keep out of the reach of children.

Contents
Each bottle contains 30 vegetarian capsules (typically a 30 day supply).

Storage
For best results, keep tightly closed and store in a cool dry place or keep refrigerated (refrigeration not required).