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What It Does
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Durable PAIN RELIEF features a clinically proven 600 mg dose of a revolutionary natural ingredient called PEA. This extra-strength dose has been found to significantly reduce back pain in just three weeks. Multiple gold-standard clinical studies have also demonstrated PEA’s ability to effectively relieve nerve-related pain and joint pain throughout your body in as little as two months.*
This next-generation pain relief formula also features 750 mg of Meriva® Curcumin Phytosome™, a super-absorbable turmeric extract that is one of nature’s secret weapons for combating pain and inflammation. Meriva® is made with cutting-edge natural phytosome technology that offers 29x better bioavailability (a measure of absorption) and 2x faster absorption, making it vastly superior to generic turmeric, which is often of poor quality and difficult to absorb.*
In addition, Durable PAIN RELIEF includes 100 mg of Gingever® ginger extract, which is standardized to 10% gingerols, for synergistic inflammation-fighting benefits.*
No other formula on the market today combines these three potent ingredients into a single convenient formula that provides unparalleled pain relief without side effects.*
This synergistic combination of powerful, clinically validated ingredients:*
- Provides fast, lasting relief from joint, muscle and nerve pain
- Significantly reduces back pain in as little as three weeks
- Relieves nerve-related pain and knee pain within two months
- Increases flexibility, mobility and range of motion
- Promotes faster recovery from exercise, injury and everyday activities
- Reduces harmful inflammation throughout the body
General Product Info:
- 60 vegetarian capsules (a 30 day supply)
- Made in the USA in an FDA inspected, cGMP facility
- Every batch is 3rd party tested for safety and purity
- Packaged in premium, non-toxic amber glass bottles
- One-year return policy with free return shipping
Why It Works
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In 20+ years of helping patients address pain and inflammation naturally, Dr. Passero has found these three ingredients to be the fastest-acting, longest-lasting and most effective. What makes them so potent is that when taken together, they work synergistically via multiple distinct mechanisms of action to help restore comfort and mobility to your entire body from head to toe.*
PEA: A Breakthrough in Natural Pain Relief (600 mg)
Palmitoylethanolamide, or PEA for short, is a fatty-acid derivative our bodies produce in response to inflammation-inducing damage that helps downregulate pain and promote healing. But the aging process—as well as prolonged periods of inflammation—deplete our body’s natural PEA stores, which is why replenishing with supplemental PEA can provide powerful relief from pain.*
Extensively studied in Europe for many years, PEA’s pain-relieving properties were discovered by Italian Nobel Prize winner Rita Levi-Montalcini, who proved its role in regulating inflammation. Today, multiple gold-standard clinical studies have established the validity of PEA as a powerful natural pain reliever for nerve, muscle and joint pain. And multiple studies show PEA works quickly—in as little three weeks—to provide significant pain relief. Notably, a large double-blind, placebo-controlled study showed that the 600 mg daily dose of PEA found in Durable PAIN RELIEF significantly reduced lower back pain in just three weeks. By the end of the three-week trial, 90% of those taking PEA reported “good or excellent” pain relief.*
A hospital study echoed these results, with 88% of patients taking PEA to relieve widespread, ongoing pain reporting “significant” score improvements in overall comfort and quality of life.*
Another study found that the same 600 mg dose of PEA significantly improved knee pain, stiffness and function in just two months.*
But while several studies have shown that PEA offers powerful muscle and joint pain relief, where it really shines is in its ability to relieve neuropathic (nerve-related) pain in as little as 1-2 months. Several studies conducted on patients with pain that was not relieved by conventional therapies have shown that a 600 mg daily dose of PEA offers significant relief of various types of neuropathic pain. The types of pain PEA was shown to relieve included back pain related to pinched nerves and wrist pain related to nerve compression in the carpal tunnel.*
Simply put, Dr. Passero feels that PEA is the most effective natural pain relief ingredient available today based on his own clinical practice and the over 20 years of research demonstrating PEA’s powerful ability to relieve body-wide pain.*
We use the highest quality PEA available on the market that has been ultra-micronized to ensure superior levels of absorption. Many brands use PEA that is poorly absorbed and provide only 200-300 mg which is not an effective, clinically backed dose*
Meriva® Curcumin Phytosome™: Harnesses Turmeric’s Full Inflammation-Fighting Potential (750 mg)
The root of the turmeric plant contains extraordinarily powerful inflammation-fighting compounds called curcuminoids, the best-known of which is curcumin.*
Gold-standard clinical studies from around the world have shown that curcumin is perhaps the most effective natural substance on earth at inhibiting COX-2, an enzyme that is responsible for sparking your body’s inflammatory response, which can lead to continuous pain and discomfort.*
Sourced from a leading Italian innovator of absorption technology, Meriva® addresses the absorption issues turmeric is notorious for with cutting-edge natural phytosome technology. Meriva® combines turmeric’s curcuminoids with phosphatidylcholine into a single, easy-to-absorb compound. This phytosome technology is a food-based delivery system, meaning that it mimics the superior absorption characteristics seen when healing compounds are naturally obtained in the diet from food.*
Meriva® is proven to offer 29x better bioavailability and 2x faster absorption of turmeric’s three most important curcuminoids compared to unformulated turmeric. And Meriva®’s curcuminoids are proven to stay in the bloodstream longer, giving them a stronger therapeutic action. Meriva® also provides the highest levels of demethoxycurcumin (DMC), turmeric’s most powerful curcuminoid, of any turmeric supplement available on the market today, offering you a powerful defense against body-wide inflammation and pain.*
Meriva® Curcumin Phytosome™ is carefully sourced from turmeric grown in pristine, nutrient-rich farmlands in India, the birthplace of both turmeric and the ancient Ayurvedic medical tradition turmeric is part of. Meriva® is tested and guaranteed to be free of over 450 pesticide residues, mold toxins and heavy metals to ensure the highest level of purity and safety possible.*
Additionally, Meriva® is the only turmeric extract endorsed by the prestigious Cleveland Clinic.*
Gingever® Ginger: Synergistically Enhances PEA and Turmeric’s Effectiveness (100 mg)
Warming and naturally anti-inflammatory, ginger has a long history of use in many natural healing traditions throughout the world. There is also extensive scientific evidence supporting its inflammation-fighting properties, largely due to the presence of bioactive compounds called gingerols, as well as other polyphenols. These potent compounds have been shown to fight oxidative stress and inhibit the production of pro-inflammatory chemicals in the body. Numerous studies have highlighted ginger's potential to reduce inflammation related to ongoing pain.*
Additionally, ginger synergistically enhances the effectiveness of the other ingredients in this formula by helping to increase absorption. Ginger is an herbal synergist that helps amplify the effects of other ingredients in a formula by supporting digestion and boosting circulation, which helps the body absorb and integrate active compounds.*
The Gingever® we use in our formula is a high-potency ginger extract standardized to deliver 10% active gingerols for maximum effectiveness. Gingever® uses supercritical CO2 extraction technology to concentrate the active compounds found in ginger without the use of harsh solvents. This extraction process also provides a rich source of ginger’s full spectrum of polyphenols in a composition similar to what is found naturally in ginger root.*
Consider Durable PAIN RELIEF PLUS® If You Struggle with Ongoing Pain and Inflammation
If you are suffering from ongoing back, wrist, knee, joint, muscle or nerve pain, we recommend that you consider our money-saving Durable PAIN RELIEF PLUS bundle, which combines Durable PAIN RELIEF with Durable TURMERIC. You can save up to $33 per 1-month supply vs. buying 1 bottle of each product separately.*
Since these two formulas address pain and underlying inflammation via different mechanisms of action, combining them provides a more comprehensive, multi-action approach. Additionally, research shows that, at a daily dose of 2,000 mg, Meriva® Curcumin Phytosome™ provides fast-acting pain relief comparable to conventional pain solutions—but without side effects. We strategically formulated Durable TURMERIC and Durable PAIN RELIEF to provide this powerful, clinically proven 2,000 mg dose of Meriva® when you take them together.*
Why We Use Amber Glass Bottles vs. Clear Glass or Plastic
- Glass is infinitely recyclable and reusable.
- Protects the ingredients from UV light damage.
- No risk of chemicals in plastics leaching into pills.
Directions & Label Information
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For adults only. Take 2 capsules once daily with food or as directed by your healthcare practitioner. For additional support, Dr. Passero recommends taking 2 capsules twice daily for the first 14 days and then reducing to the standard dose of 2 capsules once daily or consider our Durable PAIN RELIEF PLUS discounted bundle, which includes Durable TURMERIC.
Clean Formula Guarantee
Non-GMO | Gluten Free | Vegan | Dairy Free | Soy Free | Nut Free | Egg Free | Free of Artificial Colors or Preservatives
Timing of Results
Like most nutritional supplements, Durable PAIN RELIEF will take time and consistent use in order to achieve maximum effectiveness. With continuous daily use, you can expect to notice benefits in 3-8 weeks. Dr. Passero recommends taking Durable PAIN RELIEF for at least 90 days before evaluating your progress so you can make a proper assessment.*
Side Effects & Interactions
Since Durable PAIN RELIEF is made with 100% natural ingredients, the vast majority of users have no side effects, allergic reactions or interactions. It has no known interactions with most prescription drugs, medications or other dietary supplements.
Cautions
If taking medication, pregnant or breastfeeding consult your healthcare practitioner before use. Keep out of the reach of children.
Contents
Each bottle contains 60 vegetarian capsules (typically a 30 day supply).
Storage
Keep tightly closed in a cool, dry place.

Durable PAIN RELIEF®
Relieves Ongoing Aches & Pains Within Weeks
Savings based on 1 bottle price

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What It Does
+
Durable PAIN RELIEF features a clinically proven 600 mg dose of a revolutionary natural ingredient called PEA. This extra-strength dose has been found to significantly reduce back pain in just three weeks. Multiple gold-standard clinical studies have also demonstrated PEA’s ability to effectively relieve nerve-related pain and joint pain throughout your body in as little as two months.*
This next-generation pain relief formula also features 750 mg of Meriva® Curcumin Phytosome™, a super-absorbable turmeric extract that is one of nature’s secret weapons for combating pain and inflammation. Meriva® is made with cutting-edge natural phytosome technology that offers 29x better bioavailability (a measure of absorption) and 2x faster absorption, making it vastly superior to generic turmeric, which is often of poor quality and difficult to absorb.*
In addition, Durable PAIN RELIEF includes 100 mg of Gingever® ginger extract, which is standardized to 10% gingerols, for synergistic inflammation-fighting benefits.*
No other formula on the market today combines these three potent ingredients into a single convenient formula that provides unparalleled pain relief without side effects.*
This synergistic combination of powerful, clinically validated ingredients:*
- Provides fast, lasting relief from joint, muscle and nerve pain
- Significantly reduces back pain in as little as three weeks
- Relieves nerve-related pain and knee pain within two months
- Increases flexibility, mobility and range of motion
- Promotes faster recovery from exercise, injury and everyday activities
- Reduces harmful inflammation throughout the body
General Product Info:
- 60 vegetarian capsules (a 30 day supply)
- Made in the USA in an FDA inspected, cGMP facility
- Every batch is 3rd party tested for safety and purity
- Packaged in premium, non-toxic amber glass bottles
- One-year return policy with free return shipping
Why It Works
+
In 20+ years of helping patients address pain and inflammation naturally, Dr. Passero has found these three ingredients to be the fastest-acting, longest-lasting and most effective. What makes them so potent is that when taken together, they work synergistically via multiple distinct mechanisms of action to help restore comfort and mobility to your entire body from head to toe.*
PEA: A Breakthrough in Natural Pain Relief (600 mg)
Palmitoylethanolamide, or PEA for short, is a fatty-acid derivative our bodies produce in response to inflammation-inducing damage that helps downregulate pain and promote healing. But the aging process—as well as prolonged periods of inflammation—deplete our body’s natural PEA stores, which is why replenishing with supplemental PEA can provide powerful relief from pain.*
Extensively studied in Europe for many years, PEA’s pain-relieving properties were discovered by Italian Nobel Prize winner Rita Levi-Montalcini, who proved its role in regulating inflammation. Today, multiple gold-standard clinical studies have established the validity of PEA as a powerful natural pain reliever for nerve, muscle and joint pain. And multiple studies show PEA works quickly—in as little three weeks—to provide significant pain relief. Notably, a large double-blind, placebo-controlled study showed that the 600 mg daily dose of PEA found in Durable PAIN RELIEF significantly reduced lower back pain in just three weeks. By the end of the three-week trial, 90% of those taking PEA reported “good or excellent” pain relief.*
A hospital study echoed these results, with 88% of patients taking PEA to relieve widespread, ongoing pain reporting “significant” score improvements in overall comfort and quality of life.*
Another study found that the same 600 mg dose of PEA significantly improved knee pain, stiffness and function in just two months.*
But while several studies have shown that PEA offers powerful muscle and joint pain relief, where it really shines is in its ability to relieve neuropathic (nerve-related) pain in as little as 1-2 months. Several studies conducted on patients with pain that was not relieved by conventional therapies have shown that a 600 mg daily dose of PEA offers significant relief of various types of neuropathic pain. The types of pain PEA was shown to relieve included back pain related to pinched nerves and wrist pain related to nerve compression in the carpal tunnel.*
Simply put, Dr. Passero feels that PEA is the most effective natural pain relief ingredient available today based on his own clinical practice and the over 20 years of research demonstrating PEA’s powerful ability to relieve body-wide pain.*
We use the highest quality PEA available on the market that has been ultra-micronized to ensure superior levels of absorption. Many brands use PEA that is poorly absorbed and provide only 200-300 mg which is not an effective, clinically backed dose*
Meriva® Curcumin Phytosome™: Harnesses Turmeric’s Full Inflammation-Fighting Potential (750 mg)
The root of the turmeric plant contains extraordinarily powerful inflammation-fighting compounds called curcuminoids, the best-known of which is curcumin.*
Gold-standard clinical studies from around the world have shown that curcumin is perhaps the most effective natural substance on earth at inhibiting COX-2, an enzyme that is responsible for sparking your body’s inflammatory response, which can lead to continuous pain and discomfort.*
Sourced from a leading Italian innovator of absorption technology, Meriva® addresses the absorption issues turmeric is notorious for with cutting-edge natural phytosome technology. Meriva® combines turmeric’s curcuminoids with phosphatidylcholine into a single, easy-to-absorb compound. This phytosome technology is a food-based delivery system, meaning that it mimics the superior absorption characteristics seen when healing compounds are naturally obtained in the diet from food.*
Meriva® is proven to offer 29x better bioavailability and 2x faster absorption of turmeric’s three most important curcuminoids compared to unformulated turmeric. And Meriva®’s curcuminoids are proven to stay in the bloodstream longer, giving them a stronger therapeutic action. Meriva® also provides the highest levels of demethoxycurcumin (DMC), turmeric’s most powerful curcuminoid, of any turmeric supplement available on the market today, offering you a powerful defense against body-wide inflammation and pain.*
Meriva® Curcumin Phytosome™ is carefully sourced from turmeric grown in pristine, nutrient-rich farmlands in India, the birthplace of both turmeric and the ancient Ayurvedic medical tradition turmeric is part of. Meriva® is tested and guaranteed to be free of over 450 pesticide residues, mold toxins and heavy metals to ensure the highest level of purity and safety possible.*
Additionally, Meriva® is the only turmeric extract endorsed by the prestigious Cleveland Clinic.*
Gingever® Ginger: Synergistically Enhances PEA and Turmeric’s Effectiveness (100 mg)
Warming and naturally anti-inflammatory, ginger has a long history of use in many natural healing traditions throughout the world. There is also extensive scientific evidence supporting its inflammation-fighting properties, largely due to the presence of bioactive compounds called gingerols, as well as other polyphenols. These potent compounds have been shown to fight oxidative stress and inhibit the production of pro-inflammatory chemicals in the body. Numerous studies have highlighted ginger's potential to reduce inflammation related to ongoing pain.*
Additionally, ginger synergistically enhances the effectiveness of the other ingredients in this formula by helping to increase absorption. Ginger is an herbal synergist that helps amplify the effects of other ingredients in a formula by supporting digestion and boosting circulation, which helps the body absorb and integrate active compounds.*
The Gingever® we use in our formula is a high-potency ginger extract standardized to deliver 10% active gingerols for maximum effectiveness. Gingever® uses supercritical CO2 extraction technology to concentrate the active compounds found in ginger without the use of harsh solvents. This extraction process also provides a rich source of ginger’s full spectrum of polyphenols in a composition similar to what is found naturally in ginger root.*
Consider Durable PAIN RELIEF PLUS® If You Struggle with Ongoing Pain and Inflammation
If you are suffering from ongoing back, wrist, knee, joint, muscle or nerve pain, we recommend that you consider our money-saving Durable PAIN RELIEF PLUS bundle, which combines Durable PAIN RELIEF with Durable TURMERIC. You can save up to $33 per 1-month supply vs. buying 1 bottle of each product separately.*
Since these two formulas address pain and underlying inflammation via different mechanisms of action, combining them provides a more comprehensive, multi-action approach. Additionally, research shows that, at a daily dose of 2,000 mg, Meriva® Curcumin Phytosome™ provides fast-acting pain relief comparable to conventional pain solutions—but without side effects. We strategically formulated Durable TURMERIC and Durable PAIN RELIEF to provide this powerful, clinically proven 2,000 mg dose of Meriva® when you take them together.*
Why We Use Amber Glass Bottles vs. Clear Glass or Plastic
- Glass is infinitely recyclable and reusable.
- Protects the ingredients from UV light damage.
- No risk of chemicals in plastics leaching into pills.
Directions & Label Information
+
For adults only. Take 2 capsules once daily with food or as directed by your healthcare practitioner. For additional support, Dr. Passero recommends taking 2 capsules twice daily for the first 14 days and then reducing to the standard dose of 2 capsules once daily or consider our Durable PAIN RELIEF PLUS discounted bundle, which includes Durable TURMERIC.
Clean Formula Guarantee
Non-GMO | Gluten Free | Vegan | Dairy Free | Soy Free | Nut Free | Egg Free | Free of Artificial Colors or Preservatives
Timing of Results
Like most nutritional supplements, Durable PAIN RELIEF will take time and consistent use in order to achieve maximum effectiveness. With continuous daily use, you can expect to notice benefits in 3-8 weeks. Dr. Passero recommends taking Durable PAIN RELIEF for at least 90 days before evaluating your progress so you can make a proper assessment.*
Side Effects & Interactions
Since Durable PAIN RELIEF is made with 100% natural ingredients, the vast majority of users have no side effects, allergic reactions or interactions. It has no known interactions with most prescription drugs, medications or other dietary supplements.
Cautions
If taking medication, pregnant or breastfeeding consult your healthcare practitioner before use. Keep out of the reach of children.
Contents
Each bottle contains 60 vegetarian capsules (typically a 30 day supply).
Storage
Keep tightly closed in a cool, dry place.









Clinically Proven Ingredients for Unparalleled Natural Pain Relief
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Ultra-Micronized PEA
PEA is produced by our bodies in response to inflammation, but levels can get low. Increasing your PEA has been shown to provide significant back and nerve pain relief.*
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Meriva® Curcumin Phytosome™
A super-absorbable phytosome form of turmeric shown to offer 29x better absorption of turmeric’s most important pain and inflammation-fighting curcuminoids.*
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Gingever® Standardized Ginger
Standardized to provide 10% gingerols, this high-potency ginger extract synergistically enhances PEA and turmeric’s pain relief benefits.*
The Doctor Behind The Formula

Dr. Kevin Passero
Functional Medicine Expert, Licensed Naturopathic Physician and Durable Co-Founder
This precise combination of ingredients has helped many of my patients get effective pain relief when no other natural solutions worked. I firmly believe that Durable PAIN RELIEF provides the safest, most effective natural way to get pain and inflammation under control to improve mobility, flexibility and overall quality of life.
