Most Cholesterol Supplements
Are Built for One Pathway
But cholesterol isn’t one-dimensional.
It’s shaped by how multiple systems work together.
But cholesterol isn’t one-dimensional.
It’s shaped by how multiple systems
work together.
6 Min Read ⬩ Last Updated: April 2026 ⬩ Written by Dr. Kevin Passero, N.D. ⬩ Practicing Naturopathic Physician
6 Min Read ⬩ Last Updated: April 2026
Written by Dr. Kevin Passero, N.D.
Practicing Naturopathic Physician


Hello, I’m Dr. Kevin Passero.
For more than 20 years, I’ve reviewed thousands of cholesterol panels and guided patients through diet, lifestyle, natural solutions, and, when needed, conventional approaches.
And I can tell you with certainty: most cholesterol supplements simply don’t deliver meaningful results.
The reason is simple.
Most cholesterol supplements are built for one pathway.
They focus on a single number — like LDL — while ignoring how the system actually works.
But cholesterol isn’t one-dimensional.
It’s influenced by inflammation, metabolism, liver function, and more.
Yet too many products rely on generic plant powders, low-potency blends, or outdated ingredients that:
- Lack robust human clinical trials
- Require high doses that can cause side effects or poor tolerability
- Target only one pathway instead of multiple cholesterol mechanisms
- Can place strain on the liver or muscles over time
- May interfere with common medications, creating unnecessary risks
Many are underdosed, poorly formulated, or lack meaningful clinical validation altogether.
The result?
People take them for months… with little to no measurable improvement.
And it’s exactly why so many people come to me frustrated — doing everything right, but not seeing the results they expected.
Why Most Cholesterol Approaches Fall Short
Cholesterol is not just about LDL.
Your results are shaped by how multiple systems interact:
- Lipoprotein particles (ApoB)
- Inflammation (hs-CRP)
- Metabolic health (triglycerides, insulin resistance)
- Liver function
- Vascular health
When one system is off, the others follow.
That’s why targeting a single pathway often leads to limited or inconsistent results.
That’s the gap most supplements fail to address.
To solve this, I built a protocol designed to address how cholesterol actually works in your body.
My Multi-Pathway Approach to Lowering Cholesterol
My focus has always been on identifying natural solutions grounded in rigorous science that deliver consistent, measurable results for my patients.
That’s why I developed Durable CHOLESTEROL COMPLETE® — a multi-pathway formula designed to support how cholesterol actually works in the body.
It combines clinically studied nutrients, including citrus bergamot and red yeast rice, along with other synergistic ingredients to support healthy LDL, triglycerides, and HDL levels.
I’ve used this precise combination of clinically proven, plant-based ingredients in my practice for years with remarkable results, especially for my patients who need an advanced, powerful solution for severe, stubborn or genetic cholesterol issues.
It’s designed for anyone looking for a more comprehensive, natural approach to supporting their cholesterol.
By addressing multiple pathways at once, this approach is by far the fastest, safest and most effective way to lower cholesterol naturally.
And to help you get started, we’re offering 20% Off + Free Shipping on your entire order with code CHC20A.

Clinically Studied Results


Limited-Time Offer
20% Off + Free Shipping On Your Entire Order
Use Code: CHC20A
Limited-Time Offer
20% Off + Free Shipping
On Your Entire Order
Use Code: CHC20A
Better Labs or Your Money Back.
Don’t see the results you expect even after finishing the bottle?
Get a full refund within a year,
no questions asked.
Better Labs or Your Money Back.
Don’t see the results you expect even after finishing the bottle? Get a full refund within a year, no questions asked.
Coupon is one-time use. Free shipping applied at checkout.
Not valid on past orders. Cannot be combined with other promotions or rewards.
Coupon is one-time use. Free shipping applied at checkout. Not valid on past orders. Cannot be combined with other promotions or rewards.
Clinical Studies are Great – Real-Life Results are Even Better
While the results from the above clinical results are certainly impressive, it is the experiences of people like you,
who are eager to find a natural solution for lowering dangerous cholesterol and triglycerides without side effects,
that really matter.
While the results from the above clinical results are certainly impressive, it is the experiences of people like you, who are eager to find a natural solution for lowering dangerous cholesterol and triglycerides without side effects, that really matter.
How This Multi-Pathway Formula Works in Practice
Cholesterol isn’t driven by a single mechanism — it’s shaped by how multiple systems in the body work together.
Yet most supplements are built to target just one pathway — focusing on a single number like LDL while overlooking the broader system that actually determines your results.
In my clinic, I’ve seen too many patients frustrated by natural cholesterol solutions that simply don’t deliver.

They’re often underdosed, unstandardized, or built around a one-pathway approach — missing how cholesterol is actually regulated in the body.
That’s exactly why I designed Durable CHOLESTEROL COMPLETE® differently.
It’s designed to support multiple pathways at once — including lipid balance, metabolic function, inflammation, and cardiovascular health.
It’s a true multi-pathway formula — combining clinically validated ingredients at research-backed dosages to support the key systems involved in cholesterol balance.
6 Reasons This Multi-Pathway Formula Works Differently
Each ingredient in this formula is selected to support a specific pathway —
working together to address the full system behind your results.
Each ingredient in this formula is selected to support a specific pathway — working together to address the full system behind your results.
1. Bergamonte® Citrus Bergamot — Metabolic + Lipid Pathway Support
Delivers an extra-strength 1,000 mg clinical dose of patented Bergamonte®.
Shown to reduce LDL by 36% and increase HDL by 40% — while supporting blood sugar balance in as little as 30 days.*
Backed by 200+ research papers and 14 human trials.
2. 1,600 mg Organic Red Yeast Rice — Liver Pathway Support
This formula includes an extra-strength 1,600 mg dose of full-spectrum, organic, citrinin-free red yeast rice.
Supports the liver’s natural cholesterol production pathways.
In clinical studies, reduced total cholesterol by 23% and LDL by 31%. See the study →
93% of participants saw measurable improvements.
3. 50 mg Ubiqsome® CoQ10 — Cellular Energy + Cardiovascular Support
This patented phytosome CoQ10 delivers 9x better absorption than standard forms.
- Supports healthy cellular energy and cardiovascular function.
- Helps maintain healthy CoQ10 levels alongside red yeast rice. See the study →
4. 50mg Non-GMO Vitamin C — Enhanced Absorption + Antioxidant Support
- Enhances the effectiveness of citrus bergamot. See the study →
- Provides antioxidant support for cardiovascular and vascular health.
5. 100 mg Pure Olive Leaf Extract — Inflammation + Vascular Support
- Supports healthy lipid metabolism, arterial flexibility, and balanced inflammation. See the study →
- Complements Bergamonte® and organic red yeast rice to support key pathways involved in cholesterol balance.
6. Doctor-Formulated for Quality and Safety — End to End
With over 20 years of clinical experience, I designed Durable CHOLESTEROL COMPLETE to meet the highest standards of safety, purity and effectiveness:
- Clinical-grade ingredients at the dosages proven in human trials
- Clean, non-GMO formula—no fillers, dyes, or unnecessary additives
- Made in the USA in an FDA-approved, cGMP-certified facility
- Third-party tested for purity, potency and safety
- Packaged in amber glass bottles to protect against UV light and plastic leaching
- Backed by our 1-Year “Better Labs or Your Money Back” Guarantee with Free Return Shipping

Durable CHOLESTEROL COMPLETE
vs. Other Cholesterol Supplements
Limited-Time Offer
20% Off + Free Shipping On Your Entire Order
Use Code: CHC20A
Limited-Time Offer
20% Off + Free Shipping
On Your Entire Order
Use Code: CHC20A
Better Labs or Your Money Back.
Don’t see the results you expect even after finishing the bottle? Get a full refund within a year, no questions asked.
Order Now—100% Risk-FreeBetter Labs or Your Money Back.
Don’t see the results you expect even after finishing the bottle?
Get a full refund within a year,
no questions asked.
Coupon is one-time use. Free shipping applied at checkout.
Not valid on past orders. Cannot be combined with other promotions or rewards.
Coupon is one-time use. Free shipping applied at checkout. Not valid on past orders. Cannot be combined with other promotions or rewards.
Most Cholesterol Solutions Fail —
This Multi-Pathway Approach Doesn’t
Most Cholesterol Solutions Fail — This Multi-Pathway Approach Doesn’t
Within 90 days you can expect to:*
We believe in Durable CHOLESTEROL COMPLETE so strongly, it’s backed by a full 365-day guarantee with free return shipping.
If you’re not satisfied — even after finishing the bottle — you’ll get a full refund, no questions asked.
We call this our “Better Labs or Your Money Back” promise.
Within 90 days you can expect to:*
- Lower total cholesterol and LDL
- Increase HDL
- Lower triglycerides
- Reduce key inflammation markers
- Improve blood flow
- Support healthy blood sugar levels
- Improve leptin sensitivity
We believe in Durable CHOLESTEROL COMPLETE so strongly, it’s backed by a full 365-day guarantee with free return shipping.
If you’re not satisfied — even after finishing the bottle — you’ll get a full refund, no questions asked.
We call this our “Better Labs or Your Money Back” promise.
Within 90 days you can expect to:
- Lower total cholesterol and LDL
- Increase HDL
- Lower triglycerides
- Reduce key inflammation markers
- Improve blood flow
- Support healthy blood sugar levels
- Improve leptin sensitivity
20% Off + Free Shipping On Your Entire Order
Use Code: CHC20A
Limited-Time Offer
20% Off + Free Shipping
On Your Entire Order
Use Code: CHC20A
Coupon is one-time use. Free shipping applied at checkout.
Not valid on past orders. Cannot be combined with other promotions or rewards.
Coupon is one-time use. Free shipping applied at checkout. Not valid on past orders. Cannot be combined with other promotions or rewards.
About the Author
Dr. Kevin Passero, N.D.
Practicing Naturopathic Physician ‧ Chief Science Officer, Durable
Dr. Kevin Passero, N.D., is a practicing naturopathic physician with over 20 years of clinical experience in metabolic and cardiovascular health. He specializes in identifying the underlying drivers of conditions like high cholesterol, blood pressure, and insulin resistance through a systems-based approach. He has helped thousands of patients better understand their cholesterol results and develop personalized strategies to support heart health through nutrition, lifestyle, and targeted supplementation. Dr. Passero is also the Co-founder and Chief Science Officer of Durable, where he leads the development of clinically informed formulations designed to support cardiovascular and metabolic health.
























