Why Nighttime Acid Reflux Is More Serious Than You Think

Why Nighttime
Acid Reflux Is More Serious Than You Think

Why Nighttime Acid Reflux
Is More Serious Than You Think

At night, acid lingers longer—leading to more tissue damage while you sleep.

At night, acid lingers longer—leading to more tissue damage while you sleep.

At night, acid lingers longer—leading to more tissue damage while you sleep.

Last Updated: May 2026 ⬩ Written by Dr. Kevin Passero, N.D. ⬩ Practicing Naturopathic Physician

Last Updated: April 2026
Written by Dr. Kevin Passero, N.D.
Practicing Naturopathic Physician

Night Acid Reflux LP Mobile.png__PID:89017729-6293-45c8-a54d-400d49bea849Durable | Nighttime Acid Reflux

If you’re dealing with acid reflux that feels worse at night, there’s a good chance you’ve been given an incomplete explanation for why it’s happening.

Most people assume their symptoms are simply the result of something they ate earlier in the day. And while diet can play a role, it doesn’t fully explain why symptoms often become more intense the moment you lie down.

In reality, nighttime reflux is driven by a different set of conditions inside the body.

When you go from an upright position to lying flat, the digestive system loses several of its natural defenses. Gravity no longer helps keep stomach contents in place, and the mechanisms that normally help clear and neutralize acid become less active.

As a result, stomach contents can move upward more easily—and once they do, they tend to remain in contact with the esophagus longer, which can increase irritation and make symptoms feel more severe.

What Changes at Night—and Why Symptoms Get Worse

What Changes at Night—and Why Symptoms Get Worse

Hi, I’m Dr. Kevin Passero, a practicing naturopathic physician with over 20 years of clinical experience. At my clinics in the Washington, D.C. area, I’ve worked with thousands of patients struggling with acid reflux—especially those whose symptoms seem to worsen at night.

One of the most important things I explain to my patients is that nighttime reflux isn’t just a continuation of daytime symptoms. It’s driven by a different set of physiological changes that make the body less equipped to handle acid.

At Night, the body's acid defenses are largely offline:

  • Gravity no longer keeps stomach contents where they belong
  • Swallowing slows significantly, so acid is not cleared from the esophagus
  • Saliva production drops, removing the body's primary neutralizing agent
  • The esophageal lining is left more exposed for longer periods
  • Prolonged acid contact causes more tissue damage than brief daytime episodes

As a result, acid doesn’t just rise more easily—it lingers longer, placing more stress on sensitive tissue.

Why This Leads to a Self-Reinforcing Cycle

What I see repeatedly in my clinic is that nighttime reflux rarely remains an isolated issue—it becomes self-reinforcing. When symptoms disrupt sleep, the body loses the recovery time it needs to properly regulate digestive function.

That reduced recovery can make the next night’s symptoms more difficult to manage—even when nothing else has changed. Over time, many patients report that their symptoms feel more persistent and harder to control.

Reflux disrupts sleep—and poor sleep makes reflux worse.

Why Breaking the Cycle Matters

Addressing nighttime reflux effectively means doing more than reducing acid.

It requires supporting the underlying factors that drive the cycle—inflammation, mucosal irritation, and impaired digestive function—so the body can return to a more balanced state.

The Truth About Acid Blockers— And Why They Make the Problem Worse

The Truth About Acid Blockers—And Why They Make the Problem Worse

Acid-blocking drugs can silence symptoms, but they don’t repair a damaged gut lining, fix poor acid regulation, improve digestive function or reduce underlying inflammation. They also don’t correct the digestive slowdown that allows pressure to build in the first place. In fact, long-term acid suppression can create new problems—including rebound flare-ups when you try to stop.

This is why so many people feel stuck. They might experience temporary relief, but their symptoms never resolve—and may even get worse over time.

The truth is that shutting down your body’s acid production long-term with acid blockers, many of which, according to FDA guidance, are intended to be used for no longer than 14 days, can create serious issues that few doctors will warn you about. The side effects include nutrient malabsorption and increased gut permeability (leaky gut) to bone loss and increased risk of life-threatening infections. It’s a trap I make sure my patients avoid.

With millions of Americans on the wrong path, I truly believe that someday, we'll look back on the widespread and prolonged use of acid blockers as a significant medical mistake.

Durable | Shocking Dangers of Acid BlockersDurable | Shocking Dangers of Acid Blockers

There’s a Safe, Natural Alternative for Acid Reflux—Day and Night
That Works Quickly and with Incredible Efficacy

The fact that millions of people think they have no safe, alternative options for acid relief is troubling, considering that there’s a safe, natural and remarkably effective way to address the problem.

So what’s the better way? Let me walk you through the approach I use with my patients.

My natural, side-effect free regimen provides rapid symptom relief and works to relieve acid issues with four clinically proven plant-based ingredients combined with a few simple dietary and lifestyle strategies.

It’s a comprehensive, proven solution that does more than mask symptoms—it works to repair and strengthen the gut for long-lasting relief. And it has a great track record in the clinic. (It’s been so effective, I even wrote a book about it!)

My protocol makes it possible for anyone to quickly and safely put an end to acid discomfort without worrying about long-term health consequences. So if you're struggling with acid issues, please keep reading. You don't have to suffer anymore.

A Natural Approach That Works with Your Body

I’ve spent decades helping patients address their acid-related issues without relying on long-term acid suppression and dealing with its harmful consequences. My time-tested, proven strategy is a multi-layered approach that:.

  • Quickly reduces inflammation
  • Permanently heals the gut lining
  • Naturally restores microbiome balance
  • And, most importantly, allows the digestive system to function as it should

And yes, that means keeping your stomach acid at natural and appropriate levels. Because you need it—to digest food, absorb nutrients and kill harmful microbes.

Despite what your doctor or those endless commercials may tell you, suppressing acid does not solve the problem. You may experience temporary relief but later develop rebound symptoms or dangerous complications that can take years to reverse.

My approach is different, 100% natural and free of side effects. Rather than needlessly reduce acid production, I recommend supporting the tissues affected directly. My protocol quickly calms inflammation, coats and protects vulnerable tissue and gives the gut lining the nutrients it needs to repair and rebuild.

Why Other Solutions Miss the Mark

Why Other Solutions
Miss the Mark

Maybe you’ve tried other natural approaches in the past and got little benefit.

That’s because most supplements come in capsules or tablets.

They’re convenient—but ineffective, because the active ingredients don’t touch the esophagus where much of the discomfort lives.

Instead, the pill heads straight for the stomach, rendering them useless for acid relief.

Further, most supplements contain ineffective doses or unproven ingredients.

Unfortunately, if you choose the wrong supplement, it will be a total waste of time and money.

Other options, like antacids or proton pump inhibitors (PPIs), offer only a temporary patch that may bring relief, but disrupts digestion and creates the long-term dangerous risks I mentioned above.

What you really need is a solution that:

Delivers Results Without Risks

Delivers therapeutic doses of clinically proven and scientifically tested natural ingredients that are free from side effects

Direct Tissue Contact

A powder form that dissolves in water, so it coats and soothes irritated tissue un the esophagus on contact.

Targets the Root Causes

Doesn’t mask symptoms, but instead targets the root causes: inflammation, mucosal damage and  gut health

Supports Lasting Healing

Supports permanent healing of tissue in the esophagus, stomach and small intestine

The Natural Acid Relief Regimen That Has Transformed Lives

There are many natural options out there, but as I mentioned earlier, there are the four specific ingredients that form the core of the regimen I’ve prescribed to patients with acid-related digestive issues for years. They include DGL licorice, aloe vera, glutamine and zinc carnosine, and I always recommend they be taken in powder form for maximum effectiveness.

Taken together, these plant-based powerhouses synergistically provide the most effective relief—both rapid and long-term—that I’ve ever seen with zero side effects. They’ve transformed lives in my clinic, and they’re backed by research from top institutions worldwide proving their ability to:

There are many natural options out there, but as I mentioned earlier, there are the four specific ingredients that form the core of the regimen I’ve prescribed to patients with acid-related digestive issues for years. They include DGL licorice, aloe vera, glutamine and zinc carnosine, and I always recommend they be taken in powder form for maximum effectiveness.

Taken together, these plant-based powerhouses synergistically provide the most effective relief—both rapid and long-term—that I’ve ever seen with zero side effects. They’ve transformed lives in my clinic, and they’re backed by research from top institutions worldwide proving their ability to:

  • Rapidly relieve painful burning in your chest and throat
  • Reduce bloating, belching and abdominal discomfort
  • Soothe your stomach and enhance your overall digestive health
  • Improve your sleep—no more propping your head up in bed!

FINALLY—Quick, Permanent Relief with No Side Effects

Many of my patients have already tried just about every product imaginable for their acid-related digestive issues—with little relief. They’re still stuck. But when I get them on the natural regimen I’ve developed, they finally (and quickly) get the relief they’ve been seeking—permanently and with no side effects!

However, while so many of my patients achieved success with my regimen, the truth is many of them had a hard time following it. It required shopping for, purchasing and taking four different products, all in powder form.

Not only was that part of it inconvenient—it was also expensive. I knew there had to be a better solution for the patients in my clinic and anyone else looking for relief.

Fortunately, in addition to running my clinics, I also serve as Chief Science Officer for Durable®, a cutting-edge dietary supplement company that I co-founded with my good friend Josh Corn, who has been a leading natural health advocate for over 20 years.

Together we created a convenient, affordable, all-in-one solution by combining all four components of my clinic regimen into one easy, daily scoop that you mix with water—backed by over 20 years of clinical success.

We call it Durable ACID RELIEF®—and it’s priced as low as $24.95 per pouch. It also ships to you for free and includes a one-year guarantee with free return shipping.

What Durable ACID RELIEF doesn’t include is anything artificial or unnecessary. Plus, the entire formula is free of most common allergens, including gluten, dairy and soy. It’s also free of calories and naturally sweetened with monk fruit for a balanced, pleasant flavor.

Lastly, instead of cheap, chemical-laden plastic, Durable ACID RELIEF comes in a travel-friendly, plastic-free compostable pouch that preserves freshness and potency. We've also included a scooper made from plant-based plastic. 

Durable ACID RELIEF

Scientifically Formulated. Patient-Tested. Doctor-Approved.

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Doctor-Approved.

Durable ACID RELIEF is the only formula I personally recommend and use in my practice. My patients love it because it comes in a calorie-free, naturally sweetened, pleasant-tasting powder that dissolves easily in water and works fast—delivering relief right where you need it. Just one glass a day will deliver quick and lasting relief!

Unlike most supplements, Durable ACID RELIEF effectively and rapidly coats and soothes your esophagus and stomach on contact and continues to be well-absorbed by the lining of your small intestine.

And unlike the solutions your doctor may recommend, it heals and strengthens your gut instead of just masking symptoms. It's also absolutely safe for daily, long-term use and will not interact with anything else you are taking.

I’ve seen this formula change lives. I've witnessed people who have suffered for decades turn their symptoms around within 1-2 weeks and sometimes days. And now, I want you to experience what so many of my patients have: fast, safe and effective relief.

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Free shipping applied at checkout. Not valid on past orders. Cannot be combined with other promotions or rewards.

One-time use. Free shipping applied at checkout. Not valid on past orders. Cannot be combined with other promotions or rewards.

Here’s Why Durable ACID RELIEF Is Superior

1. DGL (Deglycyrrhizinated Licorice) for Fast, Proven Relief (750 mg)

Durable ACID RELIEF delivers an extra-strength, clinically validated dose of DGL in a concentrated 8:1 extract. Most supplements are made with regular, low-dose licorice extracts that are ineffective. DGL is a special form that allows for much more concentrated amounts without any of the risks associated with taking high doses of licorice.

What makes DGL so effective is that it quickly promotes mucus production and forms a protective barrier across the gastrointestinal lining. Research shows it’s extremely effective at relieving irritation in the esophagus, stomach and intestinal lining while helping to restore the integrity of these tissues over the long term.

2. Aloe Vera: Nature’s Anti-Inflammatory Soother (100 mg)

Aloe vera isn’t just a remedy for burns and skin irritation—its healing power can be incredibly effective in the digestive tract as well. In one clinical study, aloe vera reduced multiple acid-related symptoms in just two weeks—with no reported side effects. Durable ACID RELIEF includes a full, clinically proven dose of aloe vera.

The key is using a highly concentrated extract (200:1) to deliver this plant’s powerful soothing, anti-inflammatory benefits safely and effectively. Most supplements use non-concentrated doses that just don’t have the potency needed to make a difference. And the research validates this.

3. Glutamine to Heal and Strengthen Your Gut Lining (3,000 mg)

A powerful amino acid that fuels the cells of your gut lining, glutamine is one of the most effective natural substances at healing the gut by strengthening weak areas, reducing gut permeability (commonly known as leaky gut) and calming inflammation. In doing so, glutamine can also help alleviate bloating, gas and irregularity.

Additionally, glutamine has been shown to support microbiome balance and immune function. The research shows that a 3,000 mg dose of glutamine provides maximum effectiveness, and you get optimal absorption when it is in a powder form. Most supplements rely on capsules using sub-par doses of 500 mg to 1,000 mg.

4. Zinc Carnosine: A Unique and Proven Gut-Healing Compound (75 mg)

This specialized combination of zinc and carnosine has been clinically studied for its protective and healing effects on the gastrointestinal tract and for acid-related discomfort. Unlike regular zinc supplements, zinc carnosine is insoluble in saline but dissolves in acid, allowing it to stay in the stomach longer and provide targeted healing to damaged cells.

Zinc carnosine possesses unique adhesive properties, which enable it to bind to irritated stomach tissue, helping to stabilize membranes, reduce inflammation and accelerate healing of damaged cells. It’s by far the most effective form of zinc for supporting the health of the gastrointestinal system and has been used in Japan as an approved therapy for gastric issues due to its strong clinical validation.

5. Pleasant-Tasting, Quick-Dissolving Powder Delivery System

Durable ACID RELIEF is calorie-free and naturally sweetened with monk fruit instead of sugar or stevia, creating a more blanaced flavor with less aftertaste. We've also added plant-based coloring that enhances both look and taste. 

The powder dissolves quickly in water, allowing the active compounds to come into direct contact with the esophagus and stomach lining—one of the key advantages of Durable ACID RELIEF's powder delivery system.

6. Made in the USA & Lab-Tested for Quality You Can Trust

Every ingredient in Durable formulas is carefully sourced from trusted suppliers and verified for purity and potency through independent lab testing. Durable ACID RELIEF is manufactured in the U.S. in a cGMP-certified, FDA-approved facility.

7. Plastic-Free, Compostable Packaging That’s Travel-Friendly

Our plastic-free, compostable pouch keeps the powder fresh while being travel-friendly. Each pouch also includes a convenient scooper made from plant-based plastic, making your daily serving easy whether you’re at home or on the go.

8. A Great Value (with Free Shipping & Free Return Shipping)

Durable ACID RELIEF is priced as low as $24.95 per pouch (a one-month supply) and includes free shipping, free return shipping and our one-year any-reason guarantee—even if you’ve finished every last scoop!

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So How Well Does Durable ACID RELIEF Work?
Our Customers Say It Best!

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Durable ACID RELIEF Work?
Our Customers Say It Best!

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Sleeping through the night again

"I’ve tried many supplements with bad results. Acid Relief has become the answer, i'm sleeping through the night, no constant burning pain in my chest, and no more of that horrible lump in my throat."

"My husband had acid issues for over 20 years. During that time he has been on countless products. He has never experienced (almost immediately) the continued relief he is getting
from Durable ACID RELIEF."

—Holli B., Santa Rosa Beach FL

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Works great!

"I've tried for years to reduce my acid issues. Many products help a little, but not consistently. This is very reliable. I take it just once a day and never need to be concerned about acid, especially at night."

"I've tried for years to reduce my acid issues. Many products help a little, but not consistently. This is very reliable. I take it just once a day and never need to be concerned about acid, especially at night."

—Margy F., Owings Mills MD

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Excellent product

"Durable Acid Relief works better than what my doctor was telling me to take. It is such a pleasure to buy a product that works instantly.
Its a game changer!"

"Durable Acid Relief works better than what my doctor was telling me to take. It is such a pleasure to buy a product that works instantly. Its a game changer!"

—Lynn R., Monte Rio CA

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Finally able to sleep again

"Before Acid Relief, bedtime was difficult. I had reflux every night, tossing and turning for hours. Now, reflux is rare and I’m able to sleep again. This product has definitely helped me."

"My tummy has been in an uproar for months! After just one scoop I felt a difference, after 2 I feel my tummy is almost normal. No more burning, no bloated feeling. I am so pleased and happy to get back to comfort!"

—Kathy S., Hurricane WV

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Impressive results!

"My husband had acid issues for over 20 years.
During that time he has been on countless products. He has never experienced (almost immediately) the continued relief he is getting
from Durable ACID RELIEF."

"My husband had acid issues for over 20 years. During that time he has been on countless products. He has never experienced (almost immediately) the continued relief he is getting
from Durable ACID RELIEF."

—Pamela D., Westbrook CT

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Happiness

"My tummy has been in an uproar for months! After just one scoop I felt a difference, after 2 I feel my tummy is almost normal. No more burning, no bloated feeling. I am so pleased and happy
to get back to comfort!"

"My tummy has been in an uproar for months! After just one scoop I felt a difference, after 2 I feel my tummy is almost normal. No more burning, no bloated feeling. I am so pleased and happy to get back to comfort!"

—Victoria M., Mount Clemens MI

Our One Year, Any-Reason Durable ACID RELIEF Guarantee

I’m convinced Durable ACID RELIEF will be the natural, side effect-free solution you’ve been looking for.

However, if you’re not convinced Durable ACID RELIEF is making a big difference in your symptoms… or if you’re not satisfied for any reason… simply return it anytime within one year of purchase for a full refund.

No hassles, no questions asked. We even pay the return shipping. Even if you've taken every last dose, you still get a 100% refund. It’s as simple as that.

To get maximum benefits from Durable ACID RELIEF, I recommend you take it for at least 90 days. While most people notice rapid symptom relief, you can expect even greater improvements to your overall gut health within the first 15-30 days. Ordering at least 3 pouches to start gives you the chance to experience the full clinical benefits at an excellent value.

Durable ACID RELIEF Is the Solution You’ve Been Searching For!

Durable ACID RELIEF Is the Solution You’ve Been Searching For!

I'm confident that your symptoms will improve dramatically when you start using Durable ACID RELIEF—and the results will continue to get better over time. Its unique combination of ingredients is guaranteed to:

  • Rapidly relieve painful burning in your chest and throat
  • Reduce bloating, belching and abdominal discomfort
  • Soothe your stomach and enhance your overall digestive health
  • Improve your sleep—no more propping your head up in bed!
  • Be 100% free of side effects and not interact with anything else you take

I’ve seen firsthand how effectively Durable ACID RELIEF helps my patients get relief from symptoms they’ve struggled with for years. And now I’m inviting you to put it to the test yourself and see the difference it can make for you too. And with our 100% satisfaction guarantee, you can give it a complete personal test run without risking a penny!

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Limited-Time Offer

As Low As $24.95 Per Pouch + Free Shipping
(no coupon needed)

As Low As $24.95 Per Pouch
+ Free Shipping

(no coupon needed)

Order Now—100% Risk-Free

Feel the Difference or Your Money Back.

Free shipping applied at checkout. Not valid on past orders. Cannot be combined with other promotions or rewards.

One-time use. Free shipping applied at checkout. Not valid on past orders. Cannot be combined with other promotions or rewards.

About the Author

Dr. Kevin Passero, N.D.
Practicing Naturopathic Physician ‧ Chief Science Officer, Durable

Dr. Kevin Passero, N.D., is a practicing naturopathic physician with over 20 years of clinical experience in digestive and gut health. He specializes in identifying the underlying drivers of conditions like acid reflux, indigestion, and upper GI discomfort through a systems-based approach. He has helped thousands of patients better understand their symptoms and develop personalized strategies to support digestive health through nutrition, lifestyle, and targeted supplementation. Dr. Passero is also the Co-founder and Chief Science Officer of Durable, where he leads the development of clinically informed formulations designed to support digestive health and long-term relief.