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What It Does

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Your liver performs over 500 essential functions every day, one of the most important being detoxification. Dr. Passero developed Durable LIVER DETOX to provide targeted daily support for healthy liver function to help your body detoxify more effectively every day.*

Due to increasing exposure to environmental toxins, nearly everyone can benefit from improving their body’s ability to eliminate toxins. If you take medications, consume packaged foods, or drink alcohol (even moderately), you likely need additional support for healthy liver function and toxin elimination.*

Durable LIVER DETOX provides powerful daily support for optimal liver function and detoxification with Siliphos® Milk Thistle Phytosome™—a clinically proven, highly absorbable form of this time-tested liver support herb. Milk thistle forms a “shield” of protection around liver cells, neutralizing oxidative stress and strengthening liver cell membranes.*

Sourced from Italy, patented Siliphos® is backed by 13 human clinical studies and is made with cutting-edge phytosome technology for 7 times better absorption and 4 times better delivery to liver tissue. Impressively, it begins circulating through your bloodstream within minutes, reaching peak absorption in an hour. Our extra-strength 360 mg dose is double what is found in most supplements.*

Durable LIVER DETOX includes 150 mg of standardized artichoke extract, which stimulates bile production, helping the liver process fats and eliminate waste. It also features 100 mg of alpha lipoic acid, which boosts glutathione, enhancing the body’s ability to process and eliminate toxins.*

No other supplement on the market combines these effective ingredients into one convenient formula. Durable LIVER DETOX offers unparalleled support for healthy liver function and daily detoxification with just one capsule a day.*

This synergistic combination of powerful, clinically validated ingredients:*
  • Supports healthy liver function
  • Optimizes daily detoxification
  • Protects and helps regenerate liver cells
  • Helps prevent fatty deposits in the liver
  • Mitigates some of the harmful effects of alcohol
  • Promotes bile flow for efficient digestion and toxin elimination
  • Optimizes blood sugar balance and metabolic health
  • Can help make weight loss easier

General Product Info:
  • 30 vegetarian capsules (a 30 day supply)
  • Made in the USA in an FDA inspected, cGMP facility
  • Every batch is 3rd party tested for safety and purity
  • Packaged in premium, non-toxic amber glass bottles
  • One-year return policy with free return shipping

Why It Works

+
Your liver is one of the hardest-working organs in your body, performing over 500 essential functions every day, including detoxification. Drawing on 20+ years of clinical experience, Dr. Passero has found that a liver burdened by inflammation, oxidative stress or fatty deposits can quickly compromise overall health—even when symptoms are subtle.*

Your liver processes everything you consume, from food and drinks to the air you breathe, filtering out toxins and converting nutrients into usable energy. Every minute of every day, it works to keep your body detoxifying efficiently.*

Your liver also plays an essential role in producing glutathione (the body’s master antioxidant), generating bile to eliminate bilirubin, cholesterol, hormones and drugs, and metabolizing fats, proteins and carbohydrates. When these vital functions are impaired, it can lead to a range of abnormal lab results and unwanted symptoms—including elevated liver enzymes, high cholesterol, skin issues, hormonal imbalances, allergies and environmental sensitivities, and unexplained weight gain.*

In today's world, where exposure to environmental toxins is nearly unavoidable, almost everyone can benefit from strengthening the body’s natural detox pathways. While occasional cleanses can offer short-term benefits, Dr. Passero believes that a healthy lifestyle combined with daily liver support is key to reducing the long-term impact of toxic overload.*

For example, research shows that air pollution exposure can increase cardiovascular risk, largely due to oxidative stress that can build up and damage the blood vessels and arteries when the liver is overburdened. Toxin accumulation weighs down all the body’s systems and can impact how you feel day-to-day. Supporting liver health is therefore vital not only for detoxification but also for heart health and overall wellness.*

Enter Durable LIVER DETOX
Durable LIVER DETOX provides powerful daily support for optimal liver function and detoxification with Siliphos® Milk Thistle Phytosome™—a clinically proven, highly absorbable form of this time-tested liver support herb.*

Milk thistle has been proven in extensive clinical research to aid the liver in detoxifying the body by improving its ability to process and eliminate toxins. This makes it valuable for individuals exposed to environmental toxins, alcohol or certain medications.*

Backed by 13 high-quality human clinical trials on liver health, Siliphos® has been shown to normalize liver enzymes, help prevent fatty deposits in the liver and improve liver function more effectively than non-phytosome milk thistle. It’s made with cutting-edge phytosome technology shown to yield 7 times better absorption of milk thistle’s most important active constituents than standard milk thistle extracts. Siliphos® has also been shown to offer 4 times better delivery of important compounds to liver tissue.*

Sourced from a leading Italian innovator of absorption technology, Siliphos® starts to circulate important compounds through your bloodstream within minutes and reaches peak absorption in just one hour. Compared to standard silybin extracts, ours will help you get significantly better value and efficacy out of every serving.*

Additionally, our extra-strength 360 mg dose of Siliphos® Milk Thistle Phytosome™ provides roughly double the dose that is found in most milk thistle supplements.*

Durable LIVER DETOX also features a 150 mg dose of standardized artichoke extract, which helps increase bile flow to support healthy elimination of toxins. It also provides 100 mg of alpha lipoic acid, a powerful antioxidant that boosts levels of glutathione, the body’s “master antioxidant” and further enhances the liver’s ability to eliminate toxins.*

Milk Thistle Creates a Shield of Protection Around Liver Cells
Milk thistle contains multiple compounds with strong antioxidant properties that help shield liver cells from free radical damage and strengthen liver cell membranes. This protective effect creates a "shield" around your liver cells. Milk thistle also supports the liver’s natural inflammatory response to toxins and helps maintain its built-in antioxidant systems, including glutathione and superoxide dismutase (SOD).*

The primary active compound in milk thistle, silymarin, acts as an antioxidant that protects liver cells from damage caused by toxins, alcohol and other harmful substances. Silymarin not only guards liver cells but also promotes their regeneration, which is crucial for sustaining liver health.*

Silymarin has anti-inflammatory effects that help create a healthier liver environment and may lower the risk of liver-related health issues over time. And emerging research is showing that silymarin is an ally for weight loss, thanks to its ability to improve insulin signaling, lipid metabolism and gut microbiome balance.*

Among the three flavonoids in silymarin, silybin stands out as the most biologically active. Studies have shown that silybin helps protect liver cells from damage caused by substances like carbon tetrachloride, ethanol, acetaminophen, mushroom toxins and benzopyrene from automobile exhaust.*

However, silybin alone is not easily absorbed by the body. That’s where Siliphos® comes in.*

Siliphos® Milk Thistle Phytosome® Makes Silybin 7x More Absorbable (360 mg)
Italian-sourced Siliphos® consists entirely of silybin and addresses the absorption challenge by combining silybin with phosphatidylcholine in a single, easy-to-absorb compound.*

One study showed that Siliphos® Milk Thistle Phytosome™ enhances absorption of silybin by up to 7x, while another study demonstrated 4x greater delivery to liver tissue.*

Phosphatidylcholine, more than just a carrier, has its own documented liver health benefits. While silybin protects the liver through antioxidant activity, phosphatidylcholine helps repair and regenerate liver cell membranes, enhancing liver resilience.*

Artichoke Extract Enhances Bile Flow for Efficient Elimination of Toxins (150 mg)
Artichoke is a natural liver supporter that enhances bile flow, which is essential for effective digestion and detoxification.*

By stimulating bile production, artichoke extract helps the liver process fats and carry waste products into the digestive tract for elimination. Increased bile flow also reduces strain on liver cells, allowing them to focus on detoxification and cellular repair. Rich in antioxidants, artichoke extract protects liver cells from damage and supports overall liver function, making it an effective ally for promoting healthy elimination of toxins and overall digestive health.*

Our highly concentrated artichoke extract is sourced from France and standardized >=1.1% chlorogenic acid for maximum effectiveness.*

Alpha Lipoic Acid Boosts Levels of Glutathione to Enhance Liver Health (100 mg)
Alpha lipoic acid (ALA) is a powerful antioxidant that supports liver health by neutralizing oxidative stress and aiding detoxification. ALA boosts levels of glutathione, the liver’s primary detoxifier, enhancing the body’s ability to process and eliminate toxins.*

Additionally, ALA’s inflammation-fighting effects help reduce liver inflammation, and its role in improving insulin sensitivity helps regulate blood sugar, which benefits liver function. Unique among antioxidants, ALA can regenerate other antioxidants, further protecting liver cells and promoting a healthy liver environment.*

Why We Use Amber Glass Bottles vs. Clear Glass or Plastic
  • Glass is infinitely recyclable and reusable.
  • Protects the ingredients from UV light damage.
  • No risk of chemicals in plastics leaching into pills.

Directions & Label Information

+
Directions
For adults only. Take 1 capsule once daily with a meal or as directed by your healthcare practitioner. For additional liver and kidney health support, consider adding Durable TURMERIC to your daily regimen.

Clean Formula Guarantee
Non-GMO | Gluten Free | Vegan | Dairy Free | Soy Free | Nut Free | Egg Free | Free of Artificial Colors or Preservatives

Timing of Results
Like most nutritional supplements, Durable LIVER DETOX will take time and consistent use in order to achieve maximum effectiveness. With continuous daily use, you can expect to notice body-wide detoxification benefits in 4-8 weeks, with results improving over time. Dr. Passero recommends taking Durable LIVER DETOX for at least 90 days before evaluating your progress so you can make a proper assessment.

Side Effects & Interactions
Since Durable LIVER DETOX is made with 100% natural ingredients, the vast majority of users have no side effects, allergic reactions or interactions. It has no known interactions with most prescription drugs, medications or other dietary supplements.

Cautions
If you are taking medication, have a medical condition, or are pregnant or breastfeeding, consult your healthcare practitioner before use. Keep out of the reach of children.

Contents
Each bottle contains 30 vegetarian capsules (typically a 30 day supply).

Storage
Keep tightly closed in a cool, dry place.


NEW

Durable LIVER DETOX®

Powerful Daily Detoxification Support


Featuring a potent 360 mg dose of Siliphos® Milk Thistle Phytosome™—show to deliver 7x better absorption—plus standardized artichoke and alpha lipoic acid, this formula optimizes liver function for daily whole-body detoxification.*

Savings based on 1 bottle price

What It Does

+
Your liver performs over 500 essential functions every day, one of the most important being detoxification. Dr. Passero developed Durable LIVER DETOX to provide targeted daily support for healthy liver function to help your body detoxify more effectively every day.*

Due to increasing exposure to environmental toxins, nearly everyone can benefit from improving their body’s ability to eliminate toxins. If you take medications, consume packaged foods, or drink alcohol (even moderately), you likely need additional support for healthy liver function and toxin elimination.*

Durable LIVER DETOX provides powerful daily support for optimal liver function and detoxification with Siliphos® Milk Thistle Phytosome™—a clinically proven, highly absorbable form of this time-tested liver support herb. Milk thistle forms a “shield” of protection around liver cells, neutralizing oxidative stress and strengthening liver cell membranes.*

Sourced from Italy, patented Siliphos® is backed by 13 human clinical studies and is made with cutting-edge phytosome technology for 7 times better absorption and 4 times better delivery to liver tissue. Impressively, it begins circulating through your bloodstream within minutes, reaching peak absorption in an hour. Our extra-strength 360 mg dose is double what is found in most supplements.*

Durable LIVER DETOX includes 150 mg of standardized artichoke extract, which stimulates bile production, helping the liver process fats and eliminate waste. It also features 100 mg of alpha lipoic acid, which boosts glutathione, enhancing the body’s ability to process and eliminate toxins.*

No other supplement on the market combines these effective ingredients into one convenient formula. Durable LIVER DETOX offers unparalleled support for healthy liver function and daily detoxification with just one capsule a day.*

This synergistic combination of powerful, clinically validated ingredients:*
  • Supports healthy liver function
  • Optimizes daily detoxification
  • Protects and helps regenerate liver cells
  • Helps prevent fatty deposits in the liver
  • Mitigates some of the harmful effects of alcohol
  • Promotes bile flow for efficient digestion and toxin elimination
  • Optimizes blood sugar balance and metabolic health
  • Can help make weight loss easier

General Product Info:
  • 30 vegetarian capsules (a 30 day supply)
  • Made in the USA in an FDA inspected, cGMP facility
  • Every batch is 3rd party tested for safety and purity
  • Packaged in premium, non-toxic amber glass bottles
  • One-year return policy with free return shipping

Why It Works

+
Your liver is one of the hardest-working organs in your body, performing over 500 essential functions every day, including detoxification. Drawing on 20+ years of clinical experience, Dr. Passero has found that a liver burdened by inflammation, oxidative stress or fatty deposits can quickly compromise overall health—even when symptoms are subtle.*

Your liver processes everything you consume, from food and drinks to the air you breathe, filtering out toxins and converting nutrients into usable energy. Every minute of every day, it works to keep your body detoxifying efficiently.*

Your liver also plays an essential role in producing glutathione (the body’s master antioxidant), generating bile to eliminate bilirubin, cholesterol, hormones and drugs, and metabolizing fats, proteins and carbohydrates. When these vital functions are impaired, it can lead to a range of abnormal lab results and unwanted symptoms—including elevated liver enzymes, high cholesterol, skin issues, hormonal imbalances, allergies and environmental sensitivities, and unexplained weight gain.*

In today's world, where exposure to environmental toxins is nearly unavoidable, almost everyone can benefit from strengthening the body’s natural detox pathways. While occasional cleanses can offer short-term benefits, Dr. Passero believes that a healthy lifestyle combined with daily liver support is key to reducing the long-term impact of toxic overload.*

For example, research shows that air pollution exposure can increase cardiovascular risk, largely due to oxidative stress that can build up and damage the blood vessels and arteries when the liver is overburdened. Toxin accumulation weighs down all the body’s systems and can impact how you feel day-to-day. Supporting liver health is therefore vital not only for detoxification but also for heart health and overall wellness.*

Enter Durable LIVER DETOX
Durable LIVER DETOX provides powerful daily support for optimal liver function and detoxification with Siliphos® Milk Thistle Phytosome™—a clinically proven, highly absorbable form of this time-tested liver support herb.*

Milk thistle has been proven in extensive clinical research to aid the liver in detoxifying the body by improving its ability to process and eliminate toxins. This makes it valuable for individuals exposed to environmental toxins, alcohol or certain medications.*

Backed by 13 high-quality human clinical trials on liver health, Siliphos® has been shown to normalize liver enzymes, help prevent fatty deposits in the liver and improve liver function more effectively than non-phytosome milk thistle. It’s made with cutting-edge phytosome technology shown to yield 7 times better absorption of milk thistle’s most important active constituents than standard milk thistle extracts. Siliphos® has also been shown to offer 4 times better delivery of important compounds to liver tissue.*

Sourced from a leading Italian innovator of absorption technology, Siliphos® starts to circulate important compounds through your bloodstream within minutes and reaches peak absorption in just one hour. Compared to standard silybin extracts, ours will help you get significantly better value and efficacy out of every serving.*

Additionally, our extra-strength 360 mg dose of Siliphos® Milk Thistle Phytosome™ provides roughly double the dose that is found in most milk thistle supplements.*

Durable LIVER DETOX also features a 150 mg dose of standardized artichoke extract, which helps increase bile flow to support healthy elimination of toxins. It also provides 100 mg of alpha lipoic acid, a powerful antioxidant that boosts levels of glutathione, the body’s “master antioxidant” and further enhances the liver’s ability to eliminate toxins.*

Milk Thistle Creates a Shield of Protection Around Liver Cells
Milk thistle contains multiple compounds with strong antioxidant properties that help shield liver cells from free radical damage and strengthen liver cell membranes. This protective effect creates a "shield" around your liver cells. Milk thistle also supports the liver’s natural inflammatory response to toxins and helps maintain its built-in antioxidant systems, including glutathione and superoxide dismutase (SOD).*

The primary active compound in milk thistle, silymarin, acts as an antioxidant that protects liver cells from damage caused by toxins, alcohol and other harmful substances. Silymarin not only guards liver cells but also promotes their regeneration, which is crucial for sustaining liver health.*

Silymarin has anti-inflammatory effects that help create a healthier liver environment and may lower the risk of liver-related health issues over time. And emerging research is showing that silymarin is an ally for weight loss, thanks to its ability to improve insulin signaling, lipid metabolism and gut microbiome balance.*

Among the three flavonoids in silymarin, silybin stands out as the most biologically active. Studies have shown that silybin helps protect liver cells from damage caused by substances like carbon tetrachloride, ethanol, acetaminophen, mushroom toxins and benzopyrene from automobile exhaust.*

However, silybin alone is not easily absorbed by the body. That’s where Siliphos® comes in.*

Siliphos® Milk Thistle Phytosome® Makes Silybin 7x More Absorbable (360 mg)
Italian-sourced Siliphos® consists entirely of silybin and addresses the absorption challenge by combining silybin with phosphatidylcholine in a single, easy-to-absorb compound.*

One study showed that Siliphos® Milk Thistle Phytosome™ enhances absorption of silybin by up to 7x, while another study demonstrated 4x greater delivery to liver tissue.*

Phosphatidylcholine, more than just a carrier, has its own documented liver health benefits. While silybin protects the liver through antioxidant activity, phosphatidylcholine helps repair and regenerate liver cell membranes, enhancing liver resilience.*

Artichoke Extract Enhances Bile Flow for Efficient Elimination of Toxins (150 mg)
Artichoke is a natural liver supporter that enhances bile flow, which is essential for effective digestion and detoxification.*

By stimulating bile production, artichoke extract helps the liver process fats and carry waste products into the digestive tract for elimination. Increased bile flow also reduces strain on liver cells, allowing them to focus on detoxification and cellular repair. Rich in antioxidants, artichoke extract protects liver cells from damage and supports overall liver function, making it an effective ally for promoting healthy elimination of toxins and overall digestive health.*

Our highly concentrated artichoke extract is sourced from France and standardized >=1.1% chlorogenic acid for maximum effectiveness.*

Alpha Lipoic Acid Boosts Levels of Glutathione to Enhance Liver Health (100 mg)
Alpha lipoic acid (ALA) is a powerful antioxidant that supports liver health by neutralizing oxidative stress and aiding detoxification. ALA boosts levels of glutathione, the liver’s primary detoxifier, enhancing the body’s ability to process and eliminate toxins.*

Additionally, ALA’s inflammation-fighting effects help reduce liver inflammation, and its role in improving insulin sensitivity helps regulate blood sugar, which benefits liver function. Unique among antioxidants, ALA can regenerate other antioxidants, further protecting liver cells and promoting a healthy liver environment.*

Why We Use Amber Glass Bottles vs. Clear Glass or Plastic
  • Glass is infinitely recyclable and reusable.
  • Protects the ingredients from UV light damage.
  • No risk of chemicals in plastics leaching into pills.

Directions & Label Information

+
Directions
For adults only. Take 1 capsule once daily with a meal or as directed by your healthcare practitioner. For additional liver and kidney health support, consider adding Durable TURMERIC to your daily regimen.

Clean Formula Guarantee
Non-GMO | Gluten Free | Vegan | Dairy Free | Soy Free | Nut Free | Egg Free | Free of Artificial Colors or Preservatives

Timing of Results
Like most nutritional supplements, Durable LIVER DETOX will take time and consistent use in order to achieve maximum effectiveness. With continuous daily use, you can expect to notice body-wide detoxification benefits in 4-8 weeks, with results improving over time. Dr. Passero recommends taking Durable LIVER DETOX for at least 90 days before evaluating your progress so you can make a proper assessment.

Side Effects & Interactions
Since Durable LIVER DETOX is made with 100% natural ingredients, the vast majority of users have no side effects, allergic reactions or interactions. It has no known interactions with most prescription drugs, medications or other dietary supplements.

Cautions
If you are taking medication, have a medical condition, or are pregnant or breastfeeding, consult your healthcare practitioner before use. Keep out of the reach of children.

Contents
Each bottle contains 30 vegetarian capsules (typically a 30 day supply).

Storage
Keep tightly closed in a cool, dry place.


Optimize Your Liver Function for Daily Detoxification and Better Health

  • Siliphos® Milk Thistle Phytosome™

    Siliphos® Milk Thistle Phytosome™

    A super-absorbable phytosome form of milk thistle shown to offer 7x better absorption than standard milk thistle and offers powerful protection for liver cells.*

  • Standardized Artichoke Extract

    Standardized Artichoke Extract

    Highly concentrated French artichoke extract enhances bile flow, which helps the liver process fats and carry waste products into the digestive tract for elimination.*

  • Alpha Lipoic Acid (ALA)

    Alpha Lipoic Acid (ALA)

    Not only does this powerful antioxidant help neutralize oxidative stress in the liver, it also helps increase levels of glutathione, the liver’s primary detoxifier.*

The Doctor Behind The Formula

Customer Reviews

Based on 7 reviews
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(6)
14%
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M
Michele Liebal
Taking a combo

I've been taking CoQ10 for about two months, in conjunction with Durable Heart, Durable Turmeric and Durable Liver Cleanse, so I feel it's the combination of everything that has helped me to feel better.

D
Donna M. Liend
Feeling great

I got three products, Berberine, Heart and liver detox. I haven't had blood work done since I started using them, but I feel great. No more side effects. I like the way I feel, and I love going with supplements instead of the alternative.

R
RICHARD E CORSO SR
Happy

Every year when I get my blood work done it's good expect for the liver ALT and AST, the numbers are always a little high. Last year a had a ultra sound of my liver and it was good, so I don't know why the numbers are high. Around two years ago I started taking natural supplements for the liver, and I tried a lot, and nothing work to bring down the numbers. Then I tried Durable liver detox, I got my annual blood test last week and to my surprise the numbers were way down and I was real happy about that! Every time I try a supplement from Durable it works!

B
Brandon Rayner
Works Great

Switched to this product about 2 months ago and it working great. Recently had a blood test and it has helped to drop my ALT numbers.

S
Sharron Dellaporte
Wonderful

I have a friend who has taken this product and has remarkable results with his liver health and function improvement. I'm looking forward to seeing if this helps me.