The Ultimate Guide to CoQ10:
Benefits, Dosage, and Side Effects

The Ultimate Guide to CoQ10: Benefits, Dosage, and Side Effects

Plus: Why Absorption Is the Key to Choosing the Best CoQ10 Supplement

Plus: Why Absorption Is the Key to Choosing the
Best CoQ10 Supplement

What Is CoQ10?

CoQ10, short for Coenzyme Q10, is a naturally occurring, vitamin-like compound found in every cell of your body. It powers your mitochondria—the “batteries” that fuel your heart, brain, muscles, and more—while also acting as a potent antioxidant that protects against oxidative stress and aging.

Levels peak in early adulthood, then decline with age and even faster if you take medications like statins, beta-blockers, or antidepressants. That’s why CoQ10 supplementation has become one of the most researched and widely used ways to support health, energy, and longevity.

The Health Benefits of CoQ10

CoQ10 offers a wide range of health benefits across multiple body systems, making it one of the most popular nutritional supplements. Some of the top CoQ10 benefits include:

  • Heart Health: CoQ10 is essential for the health of the heart and circulatory system. It provides a key source of energy for heart muscles, protects the arteries from oxidative damage and helps regulate blood pressure.
  • Energy Production: CoQ10 is essential for proper mitochondrial function and the production of energy in every cell of the body. It can boost energy levels and muscle endurance while reducing fatigue. This is particularly essential for anyone leading an active lifestyle.
  • Antioxidant Protection: CoQ10 antioxidant-like properties fight oxidative stress throughout the body, helping to ward off many of the common health issues associated with aging.
  • Brain Health: Due to its powerful mitochondria supporting action, it plays a crucial role in supplying the high energy demands of the brain promoting memory, attention and mental clarity, while also protecting brain cells from oxidative stress.
  • Boosts Immune Function: This coenzyme supports the immune system through similar mechanisms that benefit other body systems. Its powerful antioxidant action protects immune cells and its energy promoting benefits keep the immune cells active and charged as we age. It has also been shown to reduce chronic inflammation which is a key component of healthy immune response.
  • Skin Health: CoQ10 aids in wrinkle reduction and promotes a youthful appearance due to its strong antioxidant and energy promoting properties.

CoQ10 for Statin Users

Statin drugs lower cholesterol—but also deplete CoQ10. This depletion often leads to muscle aches, weakness, and fatigue. Studies show supplementing with CoQ10 can restore levels and reduce these side effects, making it essential for anyone taking statins.

CoQ10 Dosage: How Much Should You Take?

The optimal CoQ10 dosage depends on factors such as age, health status, quality of the product and reason for supplementation. General recommendations include: 

  • For general health: 100 mg per day
  • For heart health and statin users: 100-300 mg per day

CoQ10 Side Effects and Safety

CoQ10 is generally safe and very few people experience side effects, but some people may experience mild symptoms including:

  • Digestive issues (nausea, diarrhea, upset stomach)
  • Headaches and dizziness
  • Insomnia (when taken late in the day)

Most people tolerate CoQ10 well—even at higher doses.

The Problem: Most CoQ10 Fails Due to Poor Absorption

Nearly every brand claims to be the “best CoQ10 supplement,” but few can back it up with data.

Most products rely on standard CoQ10 forms like ubiquinone, ubiquinol, or liposomal CoQ10. But these are poorly absorbed, meaning you might take 300 mg and absorb almost none of it.

It’s not just ineffective—it’s a waste of money.

The truth is, absorption matters more than dosage.

The Solution: Durable CoQ10 with Ubiqsome® + Quercefit®

While most CoQ10 supplements offer little more than a placebo, Durable CoQ10® is backed by clinical science. It uses patented Ubiqsome® Phytosome™ technology to deliver: 

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900%

better absorption
than standard CoQ10*

116%

higher blood levels
in just 2 weeks*

48+

hours of sustained
CoQ10 plasma levels*

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Advanced CoQ10 Phytosome technology delivering superior absorption to mitochondria.

What Makes Durable CoQ10 Different?

Durable CoQ10 isn’t just another supplement—it’s a scientifically engineered solution.
Here’s what sets it apart:

1. 900% Greater Absorption with Ubiqsome® CoQ10 Phytosome™

We use a 300 mg dose of Ubiqsome® CoQ10, an Italian-sourced, patented form that mimics the body’s natural delivery systems. Clinical data shows it delivers 900% better absorption than standard CoQ10—getting it deep into your cells, where it fuels energy and repair.*

2. Clinically Proven to Raise CoQ10—Fast

In peer-reviewed human studies, Ubiqsome® was shown to*:

+116% 

higher blood levels
in just 2 weeks*

Clinical Study

+36%

higher muscle CoQ10
in just 30 days*

Clinical Study

48+

hours of sustained
CoQ10 plasma levels*

Clinical Study

25%

lower oxidative stress
markers in just 1 hour*

Clinical Study

You’ll feel the difference in days, not weeks.

3. Enhanced with 2,000% Better-Absorbed Quercetin

Durable CoQ10 is the only formula combining Ubiqsome® with Quercefit®, a phytosome quercetin shown to be 20x more bioavailable than regular quercetin. Together, they amplify cardiovascular, mitochondrial, and immune support—delivering true full-body vitality. See the study →*

4. The Only CoQ10 Proven to Help Statin Users

Statins deplete CoQ10—and that’s one reason many people experience muscle pain, weakness, or fatigue.Ubiqsome® is the only form of CoQ10 clinically shown to raise muscle CoQ10 levels and significantly relieve statin-associated muscle symptoms in just 8 weeks. That’s why Durable CoQ10 is an ideal choice for anyone taking a statin or dealing with low energy. See the study →*

5. Solves the CoQ10 Absorption Problem at the Source

Durable’s Phytosome™ delivery system binds CoQ10 to sunflower lecithin for dramatically enhanced solubility, stability, and absorption—giving your body access to the benefits most CoQ10 brands can’t deliver. See the study →*

6. Doctor-Formulated to Do Better—Down to the Bottle

Created by Dr. Kevin Passero, a physician with 20+ years of experience, Durable CoQ10 delivers:

  • A clinically studied form of CoQ10  at the clinical dosage used in trials
  • A clean formula—free from fillers, dyes, or unnecessary additives
  • Made in the USA and third-party lab tested for purity
  • Packaged in amber glass to prevent plastic leaching and UV degradation
  • Backed by our 1-Year “Better Labs or Your Money Back” Guarantee

Because what goes in your body—and what it comes in—matters.

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Why Quercetin Makes CoQ10 Even Better

Most CoQ10 products don’t include quercetin—and that’s a big mistake. 

Quercetin is a powerful antioxidant that enhances CoQ10 uptake and:

  • Helps support healthy aging and cellular renewal.*
  • Supports mitochondrial health and energy in the heart, brain, liver, and muscles.*
  • Supports healthy cholesterol metabolism and transport.*
  • Helps strengthen immune defenses and improve muscle function and recovery.*
  • Provides antioxidant support to combat oxidative stress and vascular inflammation.*

But not all quercetin works. Durable CoQ10 uses Quercefit®, the only clinically proven phytosome form with up to 2,000% better absorption.

Together, Ubiqsome® + Quercefit® deliver the synergy your cells need to thrive.

Durable CoQ10 vs. Standard CoQ10

Durable vs. Standard CoQ10

Swipe to see full chart →

Durable CoQ10 (Ubiqsome®)

Standard CoQ10

Absorption

9x higher

Poor or inconsistent

Blood Level Increase

116% in 2 weeks

Minimal

Muscle Tissue Uptake

+36%

Not shown

Statin Support

Clinically proven

Rarely helps

Oxidative Stress

↓25% in 1 hour

No proof

Duration of Action

48 hours

Short-lived

Clinical Trials

Yes (multiple)

Few or none

Source

Made in Italy

Often untraceable

Trusted by Doctors. Loved by Customers.

⭐⭐⭐⭐⭐

My Cardiologist Was Surprised

"Since starting Durable CoQ10, my cardiologist has been genuinely surprised by the improvements. Beyond the product’s quality, I also want to highlight the outstanding customer service the Durable team consistently delivers."

—Alan S., Houston TX

⭐⭐⭐⭐⭐

My Doctor Recommended It

"I’ve suffered with muscle pain from my cholesterol medication, and my doctor recommended trying CoQ10. I was honestly surprised—it actually worked. For the first time in a long time, I finally have relief from the pain in my legs."

—Ruth L., Middleboro MA

⭐⭐⭐⭐⭐

Better Than Other CoQ10

"I've taken one form or another of CoQ10 for many years. Several months ago, I started taking Durable CoQ10 and have found my energy and immunity has improved substantially with no side effects."

—Minnie T., Cumming GA

⭐⭐⭐⭐⭐

I Feel a Difference

"I really do recommend this CoQ10 supplement. I have tried other brands in the past and this one I can already feel a difference and I am not even halfway through the bottle yet."

—Jeremy H., Harrison NJ

Experience the Durable Difference in Just 2 Weeks

Experience the Durable
Difference in Just 2 Weeks

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  • Clinically proven to raise CoQ10 by 116%
  • Enhances heart and muscle performance
  • Relieves statin-related aches and fatigue
  • Boosts mitochondrial and immune health
  • Supports brain clarity, endurance, and recovery

We believe in Durable CoQ10 so strongly, we back it with a 365-day, any-reason guarantee. If you’re not satisfied—even if you finish the bottle—we’ll refund your full purchase. No questions asked.

Buy Durable CoQ10 – On Sale with Free Shipping
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  • Clinically proven to raise CoQ10 by 116%
  • Enhances heart and muscle performance
  • Relieves statin-related aches and fatigue
  • Boosts mitochondrial and immune health
  • Supports brain clarity, endurance, and recovery

We believe in Durable CoQ10 so strongly, we back it with a 365-day, any-reason guarantee. If you’re not satisfied—even if you finish the bottle—we’ll refund your full purchase. No questions asked.

Buy Durable CoQ10 – On Sale + Free ShippingBuy Durable CoQ10 – On Sale
+ Free Shipping
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About Dr. Kevin Passero

Dr. Kevin Passero is a leading functional medicine expert and practicing naturopathic physician on a mission to empower people to take control of their health.

Through his two popular clinics in the Washington, DC metro area, he’s helped thousands of people find the root causes of their health imbalances and recover their energy, vitality, clarity and resilience.

Dr. Passero blends cutting-edge diagnostics with proven natural therapies to help his patients get results. He formulates every Durable supplement drawing on his over 20 years of clinical experience and the latest scientific research.

Outside of work, you can often find him enjoying the outdoors with his family.

†Dr. Kevin Passero is a licensed Naturopathic Physician in the District of Columbia and licensed Naturopathic Doctor in the State of Maryland.